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World J Diabetes. May 15, 2025; 16(5): 105549
Published online May 15, 2025. doi: 10.4239/wjd.v16.i5.105549
Anemia risk and mitigation strategies in type 2 diabetic patients: The role of novel antidiabetic agents
Petra Meliš, Maja Cigrovski Berkovic
Petra Meliš, Department for Endocrinology, Diabetes and Clinical Pharmacology, Clinical Hospital Dubrava, Zagreb 10000, Croatia
Maja Cigrovski Berkovic, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Zagreb 10000, Croatia
Co-first authors: Petra Meliš and Maja Cigrovski Berkovic.
Author contributions: Meliš P wrote and Cigrovski Berkovic M designed and edited the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maja Cigrovski Berkovic, MD, PhD, Associate Professor, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Horvacanski Zavoj 15, Zagreb 10000, Croatia. maja.cigrovskiberkovic@gmail.com
Received: January 27, 2025
Revised: March 3, 2025
Accepted: March 24, 2025
Published online: May 15, 2025
Processing time: 89 Days and 13.5 Hours
Core Tip

Core Tip: This review focuses on the overlooked prevalence and effect of anemia in type 2 diabetes, particularly in the context of chronic kidney disease. It focuses on the complicated interplay between anemia, glucose management, and diabetes-related comorbidities, as well as the possibility of emerging antidiabetic medications (sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists) to reduce anemia risk. Furthermore, the study underlines the significance of early identification of anemia and the benefits of newer antidiabetic drugs in terms of cardiovascular and kidney outcomes.