Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. May 15, 2025; 16(5): 103447
Published online May 15, 2025. doi: 10.4239/wjd.v16.i5.103447
Jejunoileal side-to-side anastomosis: New hope for patients with type 2 diabetes?
Meng-Qiu Shao, Jia-Bao Liao, Man-Yin Zhai, Qian-Qian Wan, Li-Juan Jiang, Huan-Tian Cui
Meng-Qiu Shao, Man-Yin Zhai, Huan-Tian Cui, First School of Clinical Medicine, Yunnan University of Chinese Medicine, Kunming 650000, Yunnan Province, China
Jia-Bao Liao, Department of Critical Care Medicine, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing 314000, Zhejiang Province, China
Qian-Qian Wan, Department of Medical Affairs, The First Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming 650000, Yunnan Province, China
Li-Juan Jiang, Department of Medical Ethics Committee, The First Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming 650000, Yunnan Province, China
Co-first authors: Meng-Qiu Shao and Jia-Bao Liao.
Co-corresponding authors: Li-Juan Jiang and Huan-Tian Cui.
Author contributions: Shao MQ and Liao JB conducted data searches, organized the information, and drafted the manuscript; Zhai MY and Wan QQ performed information screening and sorting; Jiang LJ and Cui HT provided conceptual inspiration, edited the manuscript, and made critical revisions for intellectual content. All authors have read and approved the final manuscript.
Conflict-of-interest statement: We declare no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Huan-Tian Cui, PhD, First School of Clinical Medicine, Yunnan University of Chinese Medicine, No. 1076 Yuhua Road, Chenggong District, Kunming 650000, Yunnan Province, China. 1762316411@qq.com
Received: November 21, 2024
Revised: February 20, 2025
Accepted: February 28, 2025
Published online: May 15, 2025
Processing time: 156 Days and 22.4 Hours
Core Tip

Core Tip: Jejunoileal side-to-side anastomosis may offer new hope for patients with type 2 diabetes. It can stimulate the production of glucagon-like peptide 1 by the terminal L cells of the ileum to control blood sugar and improve the metabolism of patients. Research shows that the procedure showed significant improvements in patients' metabolic indicators such as body mass index, blood pressure, blood glucose, insulin resistance index, and cholesterol levels at 3 and 6 months post-surgery. Of course, further investigation is needed to fully explore its indications, contraindications, the enhancement of patients’ quality of life and patients’ satisfaction with the subjective experience of treatment and long-term effects.