Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Apr 15, 2025; 16(4): 104088
Published online Apr 15, 2025. doi: 10.4239/wjd.v16.i4.104088
Analysis of risk factors and predictive value of a nomogram model for sepsis in patients with diabetic foot
Wen-Wen Han, Jian-Jiang Fang
Wen-Wen Han, Jian-Jiang Fang, Department of Emergency, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, Ningbo 315100, Zhejiang Province, China
Author contributions: Han WW designed the research, performed data curation, formal analysis, and methodology development, as well as managed resources and utilized software; Han WW also wrote the original draft of the manuscript; Fang JJ reviewed and edited the manuscript to ensure its scientific rigor and clarity, contributing critical input in refining the final draft.
Institutional review board statement: This study was approved by the Ethics Committee of Ningbo Medical Center, Lihuili Hospital.
Informed consent statement: Written informed consent for publication was obtained from all patients and/or their families included in this retrospective analysis.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: The data sets generated and analyzed during this study are not public, but under reasonable requirements, the correspondence author can provide.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Jiang Fang, MD, Department of Emergency, Ningbo Medical Center Lihuili Hospital, The Affiliated Lihuili Hospital of Ningbo University, No. 57 Xingning Road, Yinzhou District, Ningbo 315100, Zhejiang Province, China. jianjiangfan6299@yeah.net
Received: December 10, 2024
Revised: January 2, 2025
Accepted: February 7, 2025
Published online: April 15, 2025
Processing time: 81 Days and 2.8 Hours
Core Tip

Core Tip: Sepsis remains a significant complication in diabetic foot (DF) patients, often associated with poor outcomes and high mortality. However, early identification of at-risk individuals remains a clinical challenge. In our study, we identified six independent risk factors-diabetes duration, DF Texas grade, white blood cell count, glycated hemoglobin, C-reactive protein, and albumin-that contribute significantly to the risk of sepsis. We developed a nomogram incorporating these factors, demonstrating excellent diagnostic performance and clinical utility.