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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Apr 15, 2025; 16(4): 100467
Published online Apr 15, 2025. doi: 10.4239/wjd.v16.i4.100467
Published online Apr 15, 2025. doi: 10.4239/wjd.v16.i4.100467
Platelets indices clinical implications in diabetes mellitus: A broader insight
Hyder Osman Mirghani, Internal Medicine, University of Tabuk, Tabuk 51941, Saudi Arabia
Author contributions: Mirghani HO performed the conception and design of the study, the literature search, the drafting, and critical revision, and provided the final approval of the version to be published.
Conflict-of-interest statement: The author declares that there are no conflicts of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hyder Osman Mirghani, MD, Professor, Internal Medicine, University of Tabuk, Prince Fahd Bin Sultan, Tabuk 51941, Saudi Arabia. s.hyder63@hotmail.com
Received: August 19, 2024
Revised: January 6, 2025
Accepted: January 17, 2025
Published online: April 15, 2025
Processing time: 195 Days and 5.6 Hours
Revised: January 6, 2025
Accepted: January 17, 2025
Published online: April 15, 2025
Processing time: 195 Days and 5.6 Hours
Core Tip
Core Tip: Platelet indices (PIs) have been mentioned in the literature as parameters of glucoregulation. However, their clinical implications in real-world diabetes care are unclear. PIs if estimated within 2 h of blood collection could be useful and cheap indicators of glycemic control. PIs are nonspecific and affected by various patients characters. Therefore, combination with blood glucose measurement are crucial. PIs have the advantage of reflecting the previous 2 wk glycemic control compared to the glycated hemoglobin (120 d). PIs could be useful before surgery, and during pregnancy mean platelet volume and plateletcrit are more affected by confounders, and because of that platelet large cell ratio is more specific.