Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2024; 15(9): 1853-1857
Published online Sep 15, 2024. doi: 10.4239/wjd.v15.i9.1853
Inflammatory markers, oxidative stress, and mitochondrial dynamics: Repercussions on coronary artery disease in diabetes
José Carlos Tatmatsu-Rocha, Luan Santos Mendes-Costa
José Carlos Tatmatsu-Rocha, College of Medicine, Postgraduate Program in Physiotherapy and Functionality, Federal University of Ceará-UFC, Fortaleza 60430-450, Ceará, Brazil
Luan Santos Mendes-Costa, Physical Therapy, Federal University of Ceará, Fortaleza 60000-000, Ceará, Brazil
Author contributions: Tatmatsu-Rocha JC and Mendes-Costa LS contributed to this article; Tatmatsu-Rocha JC designed the overall concept and draft of the manuscript; Mendes-Costa LS contributed to the discussion and conception of the manuscript; Both authors contributed to writing and editing the manuscript and literature review.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: José Carlos Tatmatsu-Rocha, MSc, PhD, Professor, Research Scientist, College of Medicine, Postgraduate Program in Physiotherapy and Functionality, Federal University of Ceará-UFC, 1127 Coronel Nunes de Melo, Fortaleza 60430-450, Ceará, Brazil. tatmatsu@ufc.br
Received: April 3, 2024
Revised: May 11, 2024
Accepted: May 31, 2024
Published online: September 15, 2024
Processing time: 146 Days and 1.8 Hours
Core Tip

Core Tip: Increased oxidative stress promoted by pro-inflammatory mediators such as Nε-carboxymethyl-lysine causes changes in mitochondrial dynamics and has been associated with insulin resistance and cardiovascular diseases. Therapies that promote the health of mitochondria by balancing the mechanisms of mitochondrial fusion and fission may be a path forward in the context of coronary artery disease.