Randomized Controlled Trial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 15, 2024; 15(8): 1734-1741
Published online Aug 15, 2024. doi: 10.4239/wjd.v15.i8.1734
Efficacy comparison of multipoint and single point scanning panretinal laser photocoagulation in non-proliferative diabetic retinopathy treatment
Yang-Zhou Zhang, Hua Gong, Juan Yang, Ji-Pu Bu, Hui-Ling Yang
Yang-Zhou Zhang, Institute of Molecular Precision Medicine and Hunan Key Laboratory of Molecular Precision Medicine, Xiangya Hospital, Central South University,Changsha 410008, Hunan Province, China
Hua Gong, Juan Yang, Department of Ophthalmology, Xingsheng Hospital, Yiyang 413200, Hunan Province, China
Ji-Pu Bu, Department of Ophthalmology, Boshi Eye Hospital, Liuyang 410300, Hunan Province, China
Hui-Ling Yang, Department of Ophthalmology, Hunan Children‘s Hospital, Changsha 410007, Hunan Province, China
Author contributions: Zhang YZ, Gong H, Yang J, Bu JP, and Yang HL designed the research study; Zhang YZ, Gong H, and Bu JP performed the research; Zhang YZ, Gong H, and Yang J contributed new reagents and analytic tools; Zhang YZ, Bu JP, and Yang HL analyzed the data and wrote the manuscript; All authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Xiangya Hospital Central South University.
Clinical trial registration statement: This study has not yet been registered with clinical trials.
Informed consent statement: All research participants or their legal guardians provided written informed consent prior to study registration.
Conflict-of-interest statement: No conflict of interest is associated with this work.
Data sharing statement: No other data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Ling Yang, MBBS, Doctor, Department of Ophthalmology, Hunan Children‘s Hospital, No. 86 Ziyuan Road, Changsha 410007, Hunan Province, China. yanghl1211@126.com
Received: April 8, 2024
Revised: May 28, 2024
Accepted: June 27, 2024
Published online: August 15, 2024
Processing time: 108 Days and 17 Hours
Core Tip

Core Tip: This study compares the therapeutic effectiveness of multipoint and single-point scanning panretinal laser photocoagulation in non-proliferative diabetic retinopathy (NPDR) patients. The results showed that both treatment modalities had similar energy intensity and safety profiles, but the multipoint scanning mode had a lower energy density. In the short term, the multipoint scanning mode demonstrated better improvement in best-corrected visual acuity and central macular thickness compared to the single-point mode. Additionally, the multipoint mode resulted in less laser damage. These findings suggest that multipoint scanning may be a preferred treatment approach for NPDR patients.