Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jul 15, 2024; 15(7): 1645-1647
Published online Jul 15, 2024. doi: 10.4239/wjd.v15.i7.1645
Atrial fibrillation and prediabetes: A liaison that merits attention!
Akash Batta, Juniali Hatwal
Akash Batta, Department of Cardiology, Dayanand Medical College and Hospital, Ludhiana 141001, Punjab, India
Juniali Hatwal, Department of Internal Medicine, Post Graduate Institute of Medical Education & Research, Chandigarh 160012, India
Author contributions: Batta A designed, supervised, revised and approved the article; Hatwal J wrote the initial draft and revised the article; All authors have read and approved of the final version of the article.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Akash Batta, MD, Assistant Professor, Senior Scientist, Department of Cardiology, Dayanand Medical College and Hospital, Tagore Nagar, Civil Lines, Ludhiana 141001, Punjab, India. akashbatta02@gmail.com
Received: January 29, 2024
Revised: June 3, 2024
Accepted: June 18, 2024
Published online: July 15, 2024
Processing time: 160 Days and 19 Hours
Core Tip

Core Tip: Atrial fibrillation (AF) and prediabetes share common pathophysiological mechanisms with endothelial dysfunction and inflammation playing a key role. A vicious cycle is thus set up culminating in higher atherogenicity and thermogenicity of the vascular system. Desai et al retrospectively studied the impact of prediabetes amongst AF patients being admitted to hospitals following a major adverse cardiac or cerebrovascular event (MACCE). They found prediabetes to an independent risk factor for MACCE after adjusting for all confounding variables. In this letter, we appraise the study, critically analyze its clinical value and highlight the key limitations.