Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jul 15, 2024; 15(7): 1531-1536
Published online Jul 15, 2024. doi: 10.4239/wjd.v15.i7.1531
Cut-off value of glycated hemoglobin A1c for detecting diabetic retinopathy in the Chinese population
Yan Wen, Qing Wang
Yan Wen, Qing Wang, Department of Endocrinology, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China
Author contributions: Wen Y made significant contributions in the acquisition of data or in the analysis and interpretation of data; Wang Q was responsible for the overall conception of the manuscript and revised the important parts of the manuscript; and all the authors read and approved the final manuscript.
Supported by National Key R&D Program of China, No. 2016YFC1305700.
Institutional review board statement: All experimental protocols were approved by Ethics Committee of China-Japan Union Hospital of Jilin University (Approval No. 2023093021).
Informed consent statement: Informed consent was obtained from all participants and/or their legal guardian(s).
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The datasets used and/or analyzed in this study are available from the corresponding author upon reasonable request.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Qing Wang, PhD, Chief Physician, Professor, Department of Endocrinology, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun 130033, Jilin Province, China. wang_qing@jlu.edu.cn
Received: December 22, 2023
Revised: April 25, 2024
Accepted: May 23, 2024
Published online: July 15, 2024
Processing time: 199 Days and 0.9 Hours
Core Tip

Core Tip: This cross-sectional analysis of data from 887 participants in Yanbian area of China from March to April 2017 determined the best glycated hemoglobin A1c (HbA1c) cut-off point for the diagnosis of diabetic retinopathy (DR) among the Chinese population. This study implies that HbA1c is a practical diagnostic marker for DR, and an HbA1c level of 6.2% may be an appropriate cut-off value for DR detection in the Chinese population.