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World J Diabetes. Apr 15, 2024; 15(4): 623-628
Published online Apr 15, 2024. doi: 10.4239/wjd.v15.i4.623
Are treatment options used for adult-onset type 2 diabetes mellitus (equally) available and effective for children and adolescents?
Nevena Krnic, Vibor Sesa, Anna Mrzljak, Maja Cigrovski Berkovic
Nevena Krnic, Clinics for Pediatrics, University Hospital Center Zagreb, Zagreb 10000, Croatia
Vibor Sesa, Anna Mrzljak, Department of Gastroenterology and Hepatology, University Hospital Centre Zagreb, Zagreb 10000, Croatia
Anna Mrzljak, University of Zagreb School of Medicine, Zagreb 10000, Croatia
Maja Cigrovski Berkovic, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Zagreb 10000, Croatia
Author contributions: Krnic N was involved in conceptualization of the study; Cigrovski Berkovic M was responsible for data curation; Krnic N and Mrzljak A drafted the original version of the manuscript; Mrzljak A and Sesa V reviewed and edited the manuscript. All authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: All authors have no conflict of interest regarding this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Maja Cigrovski Berkovic, MD, PhD, Associate Professor, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, No. 15 Horvacanski zavoj, Zagreb 10000, Croatia. maja.cigrovskiberkovic@gmail.com
Received: December 28, 2023
Peer-review started: December 28, 2023
First decision: January 20, 2024
Revised: January 29, 2024
Accepted: March 6, 2024
Article in press: March 6, 2024
Published online: April 15, 2024
Core Tip

Core Tip: Youth-onset type 2 diabetes mellitus (T2DM) is a growing health problem. The incidence of youth-onset T2DM is especially high in overweight/obese individuals, in some ethnic groups with higher preponderance in female sex. Due to more aggressive course of T2DM in youth and earlier development of chronic complications, the stricter metabolic control targeting both glycemia and other vascular risk factors might be necessary. Newer agents with cardiovascular benefits and weight losing potential might become increasingly important in treatment of youth-onset T2DM. Moreover, future studies should focus on different approaches according to gender and use of new technologies in glucose monitoring.