Ramos-Lopez O. Genotype-based precision nutrition strategies for the prediction and clinical management of type 2 diabetes mellitus. World J Diabetes 2024; 15(2): 142-153 [PMID: 38464367 DOI: 10.4239/wjd.v15.i2.142]
Corresponding Author of This Article
Omar Ramos-Lopez, PhD, Professor, Medicine and Psychology School, Autonomous University of Baja California, Universidad 14418, UABC, Parque Internacional Industrial Tijuana, Tijuana 22390, Baja California, Mexico. oscar.omar.ramos.lopez@uabc.edu.mx
Research Domain of This Article
Genetics & Heredity
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Feb 15, 2024; 15(2): 142-153 Published online Feb 15, 2024. doi: 10.4239/wjd.v15.i2.142
Genotype-based precision nutrition strategies for the prediction and clinical management of type 2 diabetes mellitus
Omar Ramos-Lopez
Omar Ramos-Lopez, Medicine and Psychology School, Autonomous University of Baja California, Tijuana 22390, Baja California, Mexico
Author contributions: Ramos-Lopez O contributed to the writing and revision of this manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Omar Ramos-Lopez, PhD, Professor, Medicine and Psychology School, Autonomous University of Baja California, Universidad 14418, UABC, Parque Internacional Industrial Tijuana, Tijuana 22390, Baja California, Mexico. oscar.omar.ramos.lopez@uabc.edu.mx
Received: October 14, 2023 Peer-review started: October 14, 2023 First decision: December 6, 2023 Revised: December 7, 2023 Accepted: January 11, 2024 Article in press: January 11, 2024 Published online: February 15, 2024 Processing time: 112 Days and 11.1 Hours
Core Tip
Core Tip: The onset and progression of type 2 diabetes mellitus (T2DM) is influenced by complex interrelationships between genetic and dietary factors. Indeed, a number of nutrigenetic studies have identified significant gene-diet interactions related to T2DM predisposition, nutrient metabolic status, and dietary intervention responsiveness. Moreover, this knowledge has motivated the interest for the design and implementation of genotype-based dietary strategies for improving glycemic outcomes compared to conventional nutritional advice. Although more investigation is required, these insights may help to explain disease phenotype heterogeneity, with relevance in precision nutrition for the personalized prevention and clinical management of T2DM.
