Basic Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 15, 2023; 14(6): 820-845
Published online Jun 15, 2023. doi: 10.4239/wjd.v14.i6.820
Comprehensive analysis of endoplasmic reticulum stress-related mechanisms in type 2 diabetes mellitus
Bo Liang, Shu-Wen Chen, Yuan-Yuan Li, Shun-Xiao Zhang, Yan Zhang
Bo Liang, Department of Nephrology, The Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing 400037, China
Shu-Wen Chen, Yuan-Yuan Li, Shun-Xiao Zhang, Yan Zhang, Department of Endocrinology, Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 200000, China
Author contributions: Liang B and Zhang Y conceived, designed, and planned the study; Liang B, Chen SW, and Li YY analyzed the data; Liang B, Chen SW, and Zhang SX interpreted the data; Liang B drafted the manuscript; Zhang Y revised the manuscript; All authors collected the data, they all read and approved the final manuscript.
Institutional review board statement: The research does not involve ethics and animal experiments.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Publicly available datasets were analyzed in this study. This data can be found here: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166502andGPL10558.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Zhang, MD, PhD, Academic Editor, Professor, Department of Endocrinology, Shanghai Baoshan Hospital of Integrated Traditional Chinese and Western Medicine, No. 181 Youyi Road, Baoshan District, Shanghai 200000, China. yan_2999bs@163.com
Received: December 10, 2022
Peer-review started: December 10, 2022
First decision: December 26, 2022
Revised: December 27, 2022
Accepted: April 4, 2023
Article in press: April 4, 2023
Published online: June 15, 2023
Core Tip

Core Tip: This study revealed endoplasmic reticulum stress-related mechanisms in type 2 diabetes mellitus (T2DM), which might contribute to new ideas and insights for the mechanisms and treatment of T2DM.