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World J Diabetes. May 15, 2023; 14(5): 573-584
Published online May 15, 2023. doi: 10.4239/wjd.v14.i5.573
Intermediate hyperglycemia in early pregnancy: A South Asian perspective
John Punnose, Komal Sukhija, Rashika M Rijhwani
John Punnose, Department of Endocrinology and Metabolism, St. Stephen’s Hospital, Delhi 110054, India
Komal Sukhija, Rashika M Rijhwani, Department of Endocrinology, St.Stephen’s Hospital, Delhi 110054, India
Author contributions: Punnose J, Sukhija K, and Rijhwani RM contributed equally to this work; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The Authors have no conflict of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: John Punnose, MD, Dean, Department of Endocrinology and Metabolism, St. Stephen’s Hospital, Tis Hazari, Delhi 110054, India. drpunnose@rediffmail.com
Received: December 19, 2022
Peer-review started: December 19, 2022
First decision: January 17, 2023
Revised: January 28, 2023
Accepted: April 7, 2023
Article in press: April 7, 2023
Published online: May 15, 2023
Core Tip

Core Tip: Intermediate hyperglycemia in early pregnancy (IHEP) is a common metabolic disorder among South Asian pregnant women, and it accounts for one-third of women with “gestational diabetes mellitus”. The benefits of early therapeutic intervention for these women have not been established. The guidelines on the screening and management of IHEP by international and regional professional bodies are conflicting, producing major confusion in obstetric practice in South Asian countries. There is an urgent need for randomized controlled trials to settle the ongoing controversies in this field.