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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2023; 14(3): 271-278
Published online Mar 15, 2023. doi: 10.4239/wjd.v14.i3.271
Published online Mar 15, 2023. doi: 10.4239/wjd.v14.i3.271
Clinical and biochemical predictors of intensive care unit admission among patients with diabetic ketoacidosis
Adeel Ahmad Khan, Fateen Ata, Mohammed Bashir, Department of Endocrinology, Hamad Medical Corporation, Doha 00000, Qatar
Phool Iqbal, Department of Medicine, Metropolitan Hospital Center, New York, NY 10595, United States
Anand Kartha, Department of Medicine, Hamad Medical Corporation, Doha 00000, Qatar
Author contributions: Khan AA contributed to the study design, interpreted the data, and wrote the manuscript; Ata F conceptualized and designed the study, obtained ethical approval, and contributed to writing the manuscript; Iqbal P contributed to the acquisition of data and literature review; Bashir M and Kartha A are the co-last authors of the manuscript; Bashir M performed the statistical analysis and critically revised the manuscript’s content; Kartha A was the overall supervisor of the study and contributed to the study design and revision of the manuscript; all authors approved the final version of the article.
Institutional review board statement: The study was reviewed and approved by the Medical Research Center at Hamad Medical Corporation, Doha, Qatar with protocol (Approval No. MRC-01-21-476).
Informed consent statement: The requirement for participant informed consent was waived by the Medical Research Center (MRC) at Hamad Medical Corporation.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fateen Ata, MD, Doctor, Department of Endocrinology, Hamad Medical Corporation, 869 Street, Doha 00000, Qatar. docfateenata@gmail.com
Received: December 2, 2022
Peer-review started: December 2, 2022
First decision: January 3, 2023
Revised: January 13, 2023
Accepted: February 14, 2023
Article in press: February 14, 2023
Published online: March 15, 2023
Processing time: 102 Days and 16.9 Hours
Peer-review started: December 2, 2022
First decision: January 3, 2023
Revised: January 13, 2023
Accepted: February 14, 2023
Article in press: February 14, 2023
Published online: March 15, 2023
Processing time: 102 Days and 16.9 Hours
Core Tip
Core Tip: Diabetic ketoacidosis (DKA) patients requiring intensive care unit (ICU) support are older, have worse inflammatory markers, and have more severe DKA compared to those not requiring ICU admission. Older age, type 2 diabetes mellitus (T2DM), newly diagnosed DM during DKA episode, an infectious trigger of DKA, moderate-severe DKA, concurrent NSTEMI, and coronavirus disease 2019 infection are some factors that predict ICU requirement in a DKA patient.