Meta-Analysis
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Feb 15, 2023; 14(2): 120-129
Published online Feb 15, 2023. doi: 10.4239/wjd.v14.i2.120
Exposure to proton pump inhibitors and risk of diabetes: A systematic review and meta-analysis
Yun-Ran Guo, Xin-Ming Liu, Gui-Xia Wang
Yun-Ran Guo, Xin-Ming Liu, Gui-Xia Wang, Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China
Author contributions: Guo YR and Wang GX contributed to the study design; Guo YR and Liu XM conducted data collection and selection; Guo YR performed data analysis and wrote the manuscript; All authors read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest to report.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gui-Xia Wang, MD, PhD, Professor, Department of Endocrinology and Metabolism, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130000, Jilin Province, China. gwang168@jlu.edu.cn
Received: November 26, 2022
Peer-review started: November 26, 2022
First decision: December 12, 2022
Revised: December 20, 2022
Accepted: January 19, 2023
Article in press: January 19, 2023
Published online: February 15, 2023
Processing time: 80 Days and 0.4 Hours
Core Tip

Core Tip: Exposure to proton pump inhibitors has been reported to have a potential role in the development of diabetes. There are no consistent results for the association between proton pump inhibitors use and diabetes risk. This meta-analysis aimed to provide a more reliable assessment.