Wang XL, Cai FR, Gao YX, Zhang J, Zhang M. Changes and significance of retinal blood oxygen saturation and oxidative stress indexes in patients with diabetic retinopathy. World J Diabetes 2022; 13(5): 408-416 [PMID: 35664547 DOI: 10.4239/wjd.v13.i5.408]
Corresponding Author of This Article
Ming Zhang, MD, Chief Doctor, Department of Ophthalmology, West China Hospital of Sichuan University, No. 37 Guoxiang Lane, Chengdu 610000, Sichuan Province, China. mingzhangdoctor@163.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. May 15, 2022; 13(5): 408-416 Published online May 15, 2022. doi: 10.4239/wjd.v13.i5.408
Changes and significance of retinal blood oxygen saturation and oxidative stress indexes in patients with diabetic retinopathy
Xiao-Li Wang, Fang-Rong Cai, Yun-Xia Gao, Jian Zhang, Ming Zhang
Xiao-Li Wang, Fang-Rong Cai, Jian Zhang, Department of Ophthalmology, Jianyang People’s Hospital of Sichuan Province, Jianyang 641400, Sichuan Province, China
Yun-Xia Gao, Ming Zhang, Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu 610000, Sichuan Province, China
Author contributions: Wang XL and Zhang M designed this retrospective study; Wang XL and Cai FR wrote the manuscript; Wang XL, Cai FR, Gao YX and Zhang J were responsible for sorting the data; and all authors approved the final version of the article.
Institutional review board statement: The study was approved by the Ethics Committee of Jianyang People’s Hospital of Sichuan Province.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We declare no competing interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming Zhang, MD, Chief Doctor, Department of Ophthalmology, West China Hospital of Sichuan University, No. 37 Guoxiang Lane, Chengdu 610000, Sichuan Province, China. mingzhangdoctor@163.com
Received: December 13, 2021 Peer-review started: December 13, 2021 First decision: January 12, 2022 Revised: January 28, 2022 Accepted: April 28, 2022 Article in press: April 28, 2022 Published online: May 15, 2022 Processing time: 151 Days and 1.6 Hours
Core Tip
Core Tip: Diabetic retinopathy (DR) is a complication of diabetes. Studies have shown that retinal blood oxygen saturation and oxidative stress are closely associated with hypoxic-ischemic injury of retinal tissues caused by DR. Although DR treatment has improved in recent years, the long-term prognosis for late DR is not optimistic, and effective methods are needed to prevent DR from deteriorating in the later stages. Therefore, determining the incidence of DR and establishing its early diagnosis are considered clinically important. Our study monitored and analyzed retinal blood vessels, reflecting changes in serum biological indicators of blood oxygen saturation and oxidative stress levels in patients with DR, to determine the patient’s condition, thus improving the existing diagnosis and treatment methods and developing new methods for the treatment of serious complications of diabetes and subsequently ameliorating the cure rate of patients.
