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World J Diabetes. Dec 15, 2022; 13(12): 1106-1121
Published online Dec 15, 2022. doi: 10.4239/wjd.v13.i12.1106
Diabetic foot ulcers: A devastating complication of diabetes mellitus continues non-stop in spite of new medical treatment modalities
Gamze Akkus, Murat Sert
Gamze Akkus, Department of Endocrinology, Cukurova University, Adana 33170, Turkey
Murat Sert, Department of Internal Medicine, Cukurova University Medical Faculty, Adana 33170, Turkey
Author contributions: Akkus G contributed to data collection and writing; Sert M contributed to review.
Conflict-of-interest statement: There are no conflicts of interest to report.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gamze Akkus, PhD, Adjunct Associate Professor, Department of Endocrinology, Cukurova University, Sarıcam Street, Adana 33170, Turkey. tugrulgamze@hotmail.com
Received: July 21, 2022
Peer-review started: July 21, 2022
First decision: August 20, 2022
Revised: August 21, 2022
Accepted: November 18, 2022
Article in press: November 18, 2022
Published online: December 15, 2022
Core Tip

Core Tip: Diabetic foot ulcers (DFU) are one of the most common problems and devastating complications of diabetes, and affect 15% of all diabetic patients and result in significant morbidity, mortality, and financial burdens. The management of DFU is usually complex and challenging to clinicians in clinical practice. This review article aims at summarizing the etiopathogenesis and classification of DFU. It also highlights novel adjunctive treatment modalities as well as conventional management for DFU.