Review
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2022; 13(12): 1035-1048
Published online Dec 15, 2022. doi: 10.4239/wjd.v13.i12.1035
Keeping an eye on the diabetic foot: The connection between diabetic eye disease and wound healing in the lower extremity
David J Ramsey, James T Kwan, Arjun Sharma
David J Ramsey, James T Kwan, Arjun Sharma, Department of Ophthalmology, Lahey Hospital and Medical Center, Burlington, MA 01805, United States
David J Ramsey, James T Kwan, Arjun Sharma, Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, United States
Author contributions: Ramsey DJ, Kwan JT, and Sharma A contributed equally to this work; All authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: David J Ramsey, MD, PhD, Associate Professor, Director of Research, Department of Ophthalmology, Lahey Hospital and Medical Center, 41 Mall Road, Burlington, MA 01805, United States. david.j.ramsey@lahey.org
Received: August 28, 2022
Peer-review started: August 28, 2022
First decision: September 26, 2022
Revised: October 27, 2022
Accepted: November 18, 2022
Article in press: November 18, 2022
Published online: December 15, 2022
Processing time: 109 Days and 9.4 Hours
Core Tip

Core Tip: This review explores the epidemiological and pathophysiological interconnections between diabetic foot and eye disease, especially the shared mechanisms that impact wound healing. Since diabetic foot and eye problems are often concurrent, it is imperative that patients affected by one or the other condition promptly undergo reciprocal examinations to reduce the risk of further complications. The best outcomes for patients with diabetic foot and eye disease are achieved by a team-based strategy that incorporates regular examinations, often performed by specialists, provides preventative health education, and delivers effective long-term management of the underlying diabetes and its associated metabolic consequences.