Minireviews
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2021; 12(9): 1507-1517
Published online Sep 15, 2021. doi: 10.4239/wjd.v12.i9.1507
Salivary resistin level and its association with insulin resistance in obese individuals
Mona Mohamed Ibrahim Abdalla
Mona Mohamed Ibrahim Abdalla, Human Biology Department, School of Medicine, International Medical University, Kuala Lumpur 57000, Malaysia
Author contributions: Abdalla MMI collected the data and wrote the paper.
Conflict-of-interest statement: The author declares no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mona Mohamed Ibrahim Abdalla, MBBS, MSc, MD, PhD, Senior Lecturer, Human Biology Department, School of Medicine, International Medical University, 126, Jln Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur 57000, Malaysia. monamohamed@imu.edu.my
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: May 3, 2021
Revised: May 11, 2021
Accepted: July 15, 2021
Article in press: July 15, 2021
Published online: September 15, 2021
Processing time: 227 Days and 14.2 Hours
Core Tip

Core Tip: The worldwide increased prevalence of obesity-induced insulin resistance (IR) highlights the limitations of the long-term, invasive methods currently being used in detecting and monitoring IR. Measurement of salivary concentrations of adipokines such as resistin offers a good alternative to serum collection for early detection and monitoring of glycaemic control among obese individuals. However, there are conflicting findings on the association between resistin and IR. Hence this review of the available evidence aims to provide a better understanding of the role of resistin in the development of IR and the potential use of salivary resistin as a biomarker for IR.