Khandelwal R, Dassanayake AS, Conjeevaram HS, Singh SP. Non-alcoholic fatty liver disease in diabetes: When to refer to the hepatologist? World J Diabetes 2021; 12(9): 1479-1493 [PMID: PMC8472504 DOI: 10.4239/wjd.v12.i9.1479]
Corresponding Author of This Article
Shivaram P Singh, FACG, FRCP, MBBS, MD, Professor, Department of Gastroenterology, Srirama Chandra Bhanja (SCB) Medical College and Hospital, 3rd Floor, Cuttack 753007, Odisha, India. scb_gastro_dept@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Sep 15, 2021; 12(9): 1479-1493 Published online Sep 15, 2021. doi: 10.4239/wjd.v12.i9.1479
Non-alcoholic fatty liver disease in diabetes: When to refer to the hepatologist?
Reshu Khandelwal, Anuradha S Dassanayake, Hari S Conjeevaram, Shivaram P Singh
Reshu Khandelwal, Shivaram P Singh, Department of Gastroenterology, Srirama Chandra Bhanja (SCB) Medical College and Hospital, Cuttack 753007, Odisha, India
Anuradha S Dassanayake, Department of Medicine, Colombo North Centre for Liver Disease, University of Kelaniya, Kelaniya 11600, Sri Lanka
Hari S Conjeevaram, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI 48109, United States
Author contributions: Khandelwal R performed the majority of writing and prepared the table and figures; Singh SP provided input and designed the outline of this paper; Dassanayake AS and Conjeevaram HS were responsible for the revision of the manuscript and editing of the language; All authors approved the submission of the final version.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shivaram P Singh, FACG, FRCP, MBBS, MD, Professor, Department of Gastroenterology, Srirama Chandra Bhanja (SCB) Medical College and Hospital, 3rd Floor, Cuttack 753007, Odisha, India. scb_gastro_dept@hotmail.com
Received: May 17, 2021 Peer-review started: May 17, 2021 First decision: June 5, 2021 Revised: June 18, 2021 Accepted: August 3, 2021 Article in press: August 3, 2021 Published online: September 15, 2021 Processing time: 112 Days and 23.6 Hours
Core Tip
Core Tip: With prevalence of non-alcoholic fatty liver disease (NAFLD) in diabetics being substantial, there is a need for its increased awareness and knowledge in the primary care physicians and endocrinologists. It is important to understand that these patients have the propensity to develop more severe forms of liver diseases, and their early identification and management can help in providing a stitch in time. We have reviewed in detail, the currently available societal guidance on screening of NAFLD in diabetics, especially with regards to high-risk patients that require hepatologist’s referral. We have even proposed a screening protocol for these patients based on available literature. This will not only help the treating physicians in identifying the disease in its incipient stages but also help in patient’s timely referral.
