Observational Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Nov 15, 2021; 12(11): 1942-1956
Published online Nov 15, 2021. doi: 10.4239/wjd.v12.i11.1942
Adherence to Mediterranean diet and advanced glycation endproducts in patients with diabetes
Marko Grahovac, Marko Kumric, Marino Vilovic, Dinko Martinovic, Ante Kreso, Tina Ticinovic Kurir, Josip Vrdoljak, Karlo Prizmic, Joško Božić
Marko Grahovac, Department of Pharmacology, University of Split School of Medicine, Split 21000, Croatia
Marko Kumric, Marino Vilovic, Dinko Martinovic, Ante Kreso, Tina Ticinovic Kurir, Josip Vrdoljak, Karlo Prizmic, Joško Božić, Department of Pathophysiology, University of Split School of Medicine, Split 21000, Croatia
Tina Ticinovic Kurir, Department of Endocrinology, University Hospital of Split, Split 21000, Croatia
Author contributions: Grahovac M, Kumric M, Vilovic M, Ticinovic Kurir T, Martinovic D and Božić J for conceptualization, original draft preparation, and supervision; Grahovac M, Kreso A, Prizmic K, Vrdoljak J and Vilovic M for review of literature and visualization; all authors contributed to the final draft of the manuscript, have read and agreed to the published version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the Ethics Committee of University of Split School of Medicine on November 29th, 2018. (Class 003-08/18-03/0001, No. 2181-198-03-04-L8-0059).
Informed consent statement: All study participants provided informed written consent prior to the study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Joško Božić, MD, PhD, Associate Professor, Department of Pathophysiology, University of Split School of Medicine, Soltanska 2, Split 21000, Croatia. jbozic@mefst.hr
Received: May 6, 2021
Peer-review started: May 6, 2021
First decision: June 24, 2021
Revised: July 1, 2021
Accepted: October 11, 2021
Article in press: October 11, 2021
Published online: November 15, 2021
Processing time: 192 Days and 22.2 Hours
Core Tip

Core Tip: Recently, American Diabetes Association started to advocate the use of the Mediterranean diet (MD) over other diets because of its beneficial effects on glycaemic control and cardiovascular (CV) risk factors. In this cross-sectional study, we demonstrated an association between adherence to the MD and CV risk in patients with diabetes mellitus (DM) type II by measuring advanced glycation endproducts. In addition, we found that adherence to MD is very low in diabetics, especially among individuals with poorly controlled glycaemia. Finally, the duration of DM independently predicted better adherence to MD, whereas body mass index predicted poorer adherence.