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World J Diabetes. Oct 15, 2021; 12(10): 1693-1703
Published online Oct 15, 2021. doi: 10.4239/wjd.v12.i10.1693
Diabetes and gut microbiota
Yue Xi, Peng-Fei Xu
Yue Xi, Peng-Fei Xu, Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA
Peng-Fei Xu, Key Laboratory for Cell Proliferation and Regulation Biology of State Education Ministry, College of Life Sciences, Beijing Normal University, Beijing 100875, China
Author contributions: Xu PF designed the framework and supervised the preparation; Xi Y and Xu PF wrote the manuscript and prepared the figures, both authors read and approve the final manuscript.
Supported by Open Fund of Key Laboratory of Cell Proliferation and Regulation Biology, Ministry of Education, No. 201705.
Conflict-of-interest statement: Authors have nothing to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Peng-Fei Xu, PhD, Academic Research, Postdoctoral Fellow, Research Associate, Center for Pharmacogenetics and Department of Pharmaceutical Sciences, University of Pittsburgh, 323 Salk Pavilion, 335 Sutherland Drive, Pittsburgh, PA 15261, United States. pex9@pitt.edu
Received: January 24, 2021
Peer-review started: January 24, 2021
First decision: April 6, 2021
Revised: April 20, 2021
Accepted: August 5, 2021
Article in press: August 5, 2021
Published online: October 15, 2021
Processing time: 262 Days and 5.6 Hours
Core Tip

Core Tip: The current review describes the global epidemiology of diabetes in 2019 and forecasted the trends to 2030 and 2045 in China, India, USA, and globally. This review also summarizes the interaction between diabetes and the gut microbiota in three aspects: probiotics, antidiabetic medications, and diet.