Review
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. May 15, 2020; 11(5): 165-181
Published online May 15, 2020. doi: 10.4239/wjd.v11.i5.165
Fundamentals about onset and progressive disease character of type 2 diabetes mellitus
Rob NM Weijers
Rob NM Weijers, Teaching Hospital, Onze Lieve Vrouwe Gasthuis, Amsterdam 1090, Netherlands
Author contributions: Weijers RNM solely contributed to this review.
Conflict-of-interest statement: The author declares no conflict of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Rob NM Weijers, PhD, Teacher, Teaching Hospital, Onze Lieve Vrouwe Gasthuis, Oosterparkstraat 9, PO Box 95500, Amsterdam 1090, Netherlands. robw01@xs4all.nl
Received: December 20, 2019
Peer-review started: December 20, 2019
First decision: January 6, 2020
Revised: January 14, 2020
Accepted: April 8, 2020
Article in press: April 8, 2020
Published online: May 15, 2020
Processing time: 142 Days and 11.6 Hours
Core Tip

Core tip: To maximize type 2 diabetes care the assessment of unsaturation index, as observed in erythrocytes, is strongly indicated with intervals of three months. The value of unsaturation index is a reliable parameter for controlling the acyl composition of phospholipids as modulators of membrane flexibility. Given the main role of free fatty acids in this process the assessment of free fatty acids instead of triglycerides assessment may be of benefit for monthly monitoring purposes. Counseling of exercise should be an essential element of the type 2 diabetes management plan.