Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Oct 15, 2020; 11(10): 416-424
Published online Oct 15, 2020. doi: 10.4239/wjd.v11.i10.416
Published online Oct 15, 2020. doi: 10.4239/wjd.v11.i10.416
Importance of serum phosphate in elderly patients with diabetes mellitus
Vaia D Raikou, Department of Nephrology, Doctors’ Hospital, Athens 11257, Greece
Despina Kyriaki, Department of Nuclear Medicine, General Hospital “LAΪKO”, Athens 11527, Greece
Sotiris Gavriil, Department of Bariatric Surgery, Doctors’ Hospital, Athens 11257, Greece
Author contributions: Raikou VD and Gavriil S designed the research plan, data collection, biostatistic analyses and manuscript writing; Kyriaki D performed the biochemical measurements and immunoassays; all authors have read and approved the final manuscript.
Institutional review board statement: The study was approved by the ethics committee of Doctors’ Hospital (Athens, Greece).
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at vraikou@med.uoa.gr.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Corresponding author: Vaia D Raikou, PhD, Chief Doctor, Department of Nephrology, Doctors’ Hospital, 26 Kefallinias, Athens 11257, Greece. vraikou@med.uoa.gr
Received: February 4, 2020
Peer-review started: February 4, 2020
First decision: April 22, 2020
Revised: May 11, 2020
Accepted: August 25, 2020
Article in press: August 25, 2020
Published online: October 15, 2020
Processing time: 252 Days and 19.2 Hours
Peer-review started: February 4, 2020
First decision: April 22, 2020
Revised: May 11, 2020
Accepted: August 25, 2020
Article in press: August 25, 2020
Published online: October 15, 2020
Processing time: 252 Days and 19.2 Hours
Core Tip
Core Tip: Despite high serum phosphate (P) being associated with hypertension, albuminuria, smoking, low estimated glomerular filtration rate and metabolic disorders, traditional factors including older age, female gender and high body mass index were proved to be potential predictors of type 2 diabetes mellitus. Serum P levels were similar in diabetic and non-diabetic patients and the association between serum P and serum glucose or insulin resistance was found to be non-significant in both diabetic and non-diabetic patients, which was discordant with previous reports, due to renal dysfunction.