Observational Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Mar 15, 2019; 10(3): 212-223
Published online Mar 15, 2019. doi: 10.4239/wjd.v10.i3.212
Prevalence and associated factors of hospitalization for dysglycemia among elderly type 2 diabetes patients: A nationwide study
Wisit Kaewput, Charat Thongprayoon, Narittaya Varothai, Anupong Sirirungreung, Ram Rangsin, Tarun Bathini, Michael A Mao, Wisit Cheungpasitporn
Wisit Kaewput, Ram Rangsin, Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok 10400, Thailand
Charat Thongprayoon, Michael A Mao, Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN 55905, United States
Narittaya Varothai, Division of Geriatrics, Department of Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok 10400, Thailand
Anupong Sirirungreung, Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA 90095, United States
Tarun Bathini, Department of Internal Medicine, University of Arizona, Tucson, AZ 85721, United States
Wisit Cheungpasitporn, Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, United States
Author contributions: Kaewput W, Thongprayoon C and Cheungpasitporn W contributed to conceptualization; Wisit Kaewput W contributed to conceptualization data curation; Kaewput W, Thongprayoon C and Cheungpasitporn W contributed to formal analysis; Kaewput W and Thongprayoon C contributed to investigation; Kaewput W, Thongprayoon C and Cheungpasitporn W contributed to methodology; Rangsin R and Sirirungreung A contributed to project administration; Rangsin R, Varothai N, Sirirungreung A, Bathini T, Mao MA and Cheungpasitporn W contributed to supervision; Kaewput W and Thongprayoon C contributed to validation; Thongprayoon C contributed to writing – original draft; Kaewput W, Thongprayoon C, Rangsin R, Varothai N, Sirirungreung A, Bathini T, Mao MA and Cheungpasitporn W contributed to writing, review and editing.
Institutional review board statement: This study was approved by both the Institutional Review Board of the Royal Thai Army Medical Department and the Ethical Review Committee for Research in Human Subjects, the Ministry of Public Health of Thailand (IRB# S007h/54). Well-trained research nurses reviewed medical records and collected data into a case record form. Data entry into the case record form was then transferred to the central data management of the Medical Research Network of the Consortium of Thai Medical Schools to adjudicate that the process of data collection was compiled according to study protocol. The data management team was responsible for inquiries to study sites to verify data. Site monitoring was randomly performed in approximately 10% of study sites.
Informed consent statement: Patients were all patients were recruited from the outpatient clinic. Written informed consent was obtained from patients before enrolment.
Conflict-of-interest statement: The authors deny any conflict of interest.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Wisit Kaewput, MD, Academic Fellow, Assistant Professor, Doctor, Physician, Department of Military and Community Medicine, Phramongkutklao College of Medicine, 315 Ratchawithi Rd, Chang Wat, Bangkok 10400, Thailand. wisitnephro@gmail.com
Telephone: +66-235-4760093613 Fax: +66-235-47733
Received: February 14, 2019
Peer-review started: February 14, 2019
First decision: February 26, 2019
Revised: March 6, 2019
Accepted: March 11, 2019
Article in press: March 11, 2019
Published online: March 15, 2019
Processing time: 30 Days and 2.7 Hours
Core Tip

Core tip: Currently, the numbers of older individuals over 65 years of age with type 2 diabetes mellitus (T2DM) are rising. However, data of treatment-related complication especially, dysglycemia-related hospitalization is lack. In this study, we conducted a nationwide cross-sectional study based on the DM/HT study of the Medical Research Network of the Consortium of Thai Medical Schools. We demonstrated that the prevalence of dysglycemia-related hospitalization in elderly T2DM patients in Thailand was 4.9%. The close monitoring of blood glucose should be provided in high-risk patients for prevention and early detection for these complications.