Zhu XX, Yao KF, Huang HY, Wang LH. Associations between Geriatric Nutrition Risk Index, bone mineral density and body composition in type 2 diabetes patients. World J Diabetes 2024; 15(3): 403-417 [PMID: 38591073 DOI: 10.4239/wjd.v15.i3.403]
Corresponding Author of This Article
Li-Hua Wang, MNurs, Chief Nurse, Department of Nursing, The Second Affiliated Hospital of Nantong University, First People’s Hospital of Nantong City, No. 666 Shengli Road, Nantong 226001, Jiangsu Province, China. wlh512512@163.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Mar 15, 2024; 15(3): 403-417 Published online Mar 15, 2024. doi: 10.4239/wjd.v15.i3.403
Associations between Geriatric Nutrition Risk Index, bone mineral density and body composition in type 2 diabetes patients
Xiao-Xiao Zhu, Kai-Feng Yao, Hai-Yan Huang, Li-Hua Wang
Xiao-Xiao Zhu, Department of Pediatrics, The Second Affiliated Hospital of Nantong University, First People’s Hospital of Nantong City, Nantong 226001, Jiangsu Province, China
Kai-Feng Yao, Li-Hua Wang, Department of Nursing, The Second Affiliated Hospital of Nantong University, First People’s Hospital of Nantong City, Nantong 226001, Jiangsu Province, China
Hai-Yan Huang, Department of Endocrinology, The Second Affiliated Hospital of Nantong University, First People’s Hospital of Nantong City, Nantong 226001, Jiangsu Province, China
Author contributions: Zhu XX and Wang LH designed the research; Zhu XX and Yao KF collected the data; Zhu XX and Huang HY analyzed the data; Zhu XX and Yao KF wrote the paper; Wang LH reviewed the paper.
Supported bySocial Development Projects of Nantong, No. MS22021008 and No. QNZ2022005.
Institutional review board statement: The study was approved by the institutional review board of The Second Affiliated Hospital of Nantong University, First People’s Hospital of Nantong City (approval number: 2021KT063).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the Authors have no conflict of interest related to the manuscript.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Hua Wang, MNurs, Chief Nurse, Department of Nursing, The Second Affiliated Hospital of Nantong University, First People’s Hospital of Nantong City, No. 666 Shengli Road, Nantong 226001, Jiangsu Province, China. wlh512512@163.com
Received: August 24, 2023 Peer-review started: August 24, 2023 First decision: November 21, 2023 Revised: December 8, 2023 Accepted: January 24, 2024 Article in press: January 24, 2024 Published online: March 15, 2024 Processing time: 204 Days and 7.8 Hours
ARTICLE HIGHLIGHTS
Research background
In people with type 2 diabetes mellitus (T2DM), the association between nutrition, sarcopenia, and osteoporosis has rarely been explored.
Research motivation
The relationship between nutritional status and bone mass has been observed in different populations, including individuals with chronic obstructive pulmonary disease, rheumatoid arthritis, and end-stage renal disease.
Research objectives
Assess the associations among nutrition, bone mineral density (BMD) and body composition in patients with T2DM.
Research methods
A total of 689 patients with T2DM were included to perform a retrospective analysis. The general information and biochemical indices of these patients were statistically analyzed.
Research results
Those who had a high Geriatric Nutritional Risk Index (GNRI) tended to be younger and had lower HbA1c, higher BMD at all bone sites, and higher appendicular skeletal muscle index.
Research conclusions
Poor nutrition, as indicated by a low GNRI, was associated with low levels of ASMI and BMD at all bone sites in type 2 diabetes mellitus patients.
Research perspectives
We used a retrospective study to explore the association between nutrition, sarcopenia, and osteoporosis in patients with T2DM.
