Castaneda A, Jauregui-Maldonado E, Ratnani I, Varon J, Surani S. Correlation between metabolic syndrome and sleep apnea. World J Diabetes 2018; 9(4): 66-71 [PMID: 29765510 DOI: 10.4239/wjd.v9.i4.66]
Corresponding Author of This Article
Salim Surani, MD, MPH, FAASM, Adjunct Professor, Division of Pulmonary, Critical Care and Sleep Medicine, Texas A and M University, Health Science Center, 701 Ayers Street, Corpus Christi, TX 78404, United States. srsurani@hotmail.com
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Apr 15, 2018; 9(4): 66-71 Published online Apr 15, 2018. doi: 10.4239/wjd.v9.i4.66
Correlation between metabolic syndrome and sleep apnea
Alejandro Castaneda, Edgar Jauregui-Maldonado, Iqbal Ratnani, Joseph Varon, Salim Surani
Alejandro Castaneda, Edgar Jauregui-Maldonado, Dorrington Medical Associates, Houston, TX 77030, United States
Iqbal Ratnani, DeBakey Heart and Vascular Center, Houston Methodist, Houston, TX 77030, United States
Joseph Varon, Department of Acute and Continuing Care. The University of Texas Health Science Center Houston, TX 77030, United States
Salim Surani, Division of Pulmonary, Critical Care and Sleep Medicine, Texas A and M University, Health Science Center, Corpus Christi, TX 78404, United States
Author contributions: Castaneda A and Jauregui-Maldonado E were involved in the preparation of the manuscript; Ratnani I, Varon J and Surani S were involved in concept generation, preparation and review of the article.
Conflict-of-interest statement: There is no declared competing conflict of interest between authors.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Salim Surani, MD, MPH, FAASM, Adjunct Professor, Division of Pulmonary, Critical Care and Sleep Medicine, Texas A and M University, Health Science Center, 701 Ayers Street, Corpus Christi, TX 78404, United States. srsurani@hotmail.com
Telephone: +1-361-8857722 Fax: +1-361-8507563
Received: March 19, 2018 Peer-review started: March 20, 2018 First decision: April 2, 2018 Revised: April 9, 2018 Accepted: April 12, 2018 Article in press: April 12, 2018 Published online: April 15, 2018
Abstract
The so-called “metabolic syndrome” (MS), constitutes a cluster of metabolic and cardiovascular abnormalities, including fasting glucose, blood pressure, triglycerides, high density lipoprotein cholesterol (HDL-C), and waist circumference that arise from insulin resistance. Obstructive sleep apnea (OSA) syndrome is characterized by recurrent episodes of partial or complete obstruction of the upper airway, involving cessation or significant decreased airflow, with intermittent hypoxemia, frequent arousals from sleep and recurrent oxyhemoglobin desaturations that interfere with normal sleep patterns generating difficulty falling asleep, unrefreshing sleep and loud snoring. The relation between these two entities is known as “Syndrome Z”, and there is no question about the impact of these risk factors on health and disease. This clinical condition presents a growing epidemic Worldwide, affecting approximately 60% of the general population with both MS and OSA due to the constant increase of body mass index in humans. This article presents evidence-based data that focuses on the direct relationship between MS and OSA.
Core tip: Obstructive sleep apnea (OSA), has been tightly-related to several components of metabolic syndrome (MS). However, most of the evidence documented has only evaluated individual components of the MS, or patients with a diagnosis of OSA.
