Liu SQ, Wang D, Tang CC. Association between age at diagnosis of diabetes and ocular disease: Insights from a recent article. World J Diabetes 2025; 16(1): 94846 [DOI: 10.4239/wjd.v16.i1.94846]
Corresponding Author of This Article
Dong Wang, PhD, Research Assistant, Department of Cardiology, Zhongda Hospital, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing 210009, Jiangsu Province, China. wangdong_seu@163.com
Research Domain of This Article
Ophthalmology
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Jan 15, 2025; 16(1): 94846 Published online Jan 15, 2025. doi: 10.4239/wjd.v16.i1.94846
Association between age at diagnosis of diabetes and ocular disease: Insights from a recent article
Shi-Qi Liu, Dong Wang, Cheng-Chun Tang
Shi-Qi Liu, Dong Wang, Cheng-Chun Tang, Department of Cardiology, Zhongda Hospital, Southeast University, Nanjing 210009, Jiangsu Province, China
Shi-Qi Liu, Dong Wang, Cheng-Chun Tang, School of Medicine, Southeast University, Nanjing 210009, Jiangsu Province, China
Co-corresponding authors: Dong Wang and Cheng-Chun Tang.
Author contributions: Liu SQ, Wang D, and Tang CC conceived, designed, and refined this review; Liu SQ drafted the manuscript; Wang D and Tang CC contributed equally to this work as co-corresponding authors. The reasons for designating Wang D and Tang CC as co-corresponding authors are as follows. First, they both participated in choosing the idea of the study. Second, they both revised the manuscript. Third, they are both responsible for the study. In summary, we believe that designating Wang D and Tang CC as co-corresponding authors of is fitting for our manuscript as it accurately reflects our team’s collaborative spirit, equal contributions, and diversity.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dong Wang, PhD, Research Assistant, Department of Cardiology, Zhongda Hospital, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing 210009, Jiangsu Province, China. wangdong_seu@163.com
Received: March 26, 2024 Revised: September 19, 2024 Accepted: November 1, 2024 Published online: January 15, 2025 Processing time: 248 Days and 15.6 Hours
Abstract
In this article, we discuss Ye et al's recent article on the association between age at diabetes diagnosis and subsequent risk of age-related ocular diseases. The study, which utilized United Kingdom Biobank data, highlighted a strong link between early diabetes onset and major eye conditions, such as cataracts, glaucoma, age-related macular degeneration, and vision loss, independent of glycemic control and disease duration. This finding challenges the previous belief that diabetic eye disease primarily correlates with hyperglycemia. As lifestyles evolve and the age of diabetes diagnosis decreases, understanding this relationship may reveal the complex pathogenesis underlying diabetes-related complications. This editorial summarizes potential mechanisms connecting the age of diabetes onset with four types of ocular diseases, emphasizing the significance of early diagnosis.
Core Tip: The risk of eye diseases, including cataracts, glaucoma, age-related macular degeneration and vision loss, may be greater among patients who are younger at the time of diabetes diagnosis. Younger patients at the time of diabetes diagnosis may have more severe pathogenicity and refractoriness, which provides some guidance for screening diabetic patients for eye disease. This article reviews the mechanism underlying the occurrence and development of diabetes and eye diseases and the role of age at the time of diabetes diagnosis.
