Meta-Analysis
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Apr 15, 2024; 15(4): 783-792
Published online Apr 15, 2024. doi: 10.4239/wjd.v15.i4.783
Application of three-dimensional speckle tracking technique in measuring left ventricular myocardial function in patients with diabetes
Zheng Li, Ying Qian, Chun-Yun Fan, Yong Huang
Zheng Li, Ying Qian, Chun-Yun Fan, Department of Ultrasound, The People’s Hospital of Danyang, Danyang Hospital of Nantong University, Danyang 212300, Jiangsu Province, China
Yong Huang, Department of Endocrinology, The People’s Hospital of Danyang, Danyang Hospital of Nantong University, Danyang 212300, Jiangsu Province, China
Author contributions: Li Z and Qian Y were responsible for the study concept and designed the systematic review protocol; Qian Y and Huang Y performed the study selection and data extraction; Li Z and Fan CY performed the statistical analyses; Qian Y and Huang Y prepared the outlines and wrote the manuscript; and all the authors have contributed to the completion of this paper.
Conflict-of-interest statement: No conflicts of interest exit in the submission of this manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yong Huang, MM, Department of Endocrinology, The People’s Hospital of Danyang, Danyang Hospital of Nantong University, No. 2 Xinmin West Road, Danyang 212300, Jiangsu Province, China. dysrmyyhy@163.com
Received: December 5, 2023
Peer-review started: December 5, 2023
First decision: December 18, 2023
Revised: December 28, 2023
Accepted: March 7, 2024
Article in press: March 7, 2024
Published online: April 15, 2024
Abstract
BACKGROUND

Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus (DM). Therefore, early detection of left ventricular systolic function (LVSF) damage in DM is essential.

AIM

To explore the use of the three-dimensional speckle tracking technique (3D-STI) for measuring LVSF in DM patients via meta-analysis.

METHODS

The electronic databases were retrieved from the initial accessible time to 29 April 2023. The current study involved 9 studies, including 970 subjects. We carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by 3D-STI.

RESULTS

Night articles including 970 subjects were included. No significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group (P > 0.05), while differences in global longitudinal strain, global circumferential strain, global radial strain, and global area strain were markedly different between the controls and DM patients (all P < 0.05).

CONCLUSION

The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.

Keywords: Diabetes mellitus, Left ventricular systolic dysfunction, Three-dimensional speckle tracking echocardiography, Meta analysis

Core Tip: In this study, we found that three-dimensional speckle tracking technique (3D-STI) could precisely assess early left ventricular systolic dysfunction in diabetes mellitus (DM). Our meta-analysis indicated that global longitudinal strain (GLS), global radial strain, global circumferential strain, and global area strain (GAS) in DMs were lower than controls, suggesting that the left ventricular systolic function in DMs was impaired compared with controls. Among them, the decrease of GLS and GAS was more obvious, which may be since the left ventricular wall is composed of three layers of myocardial fibers. The assessment of left ventricular strain in DM patients through 3D-STI might estimate the damage of left ventricular systolic function in DM in the early stage.