Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2024; 15(12): 2293-2301
Published online Dec 15, 2024. doi: 10.4239/wjd.v15.i12.2293
Application value of high-pressure-resistant peripherally inserted central catheters in enhanced computer tomography of diabetic patients with malignant tumors
Li Zhang, Hui-Feng Yan
Li Zhang, Department of Comprehensive Interventional, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China
Hui-Feng Yan, Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College (Jiangxi Provincial Key Laboratory of Intelligent Medical Imaging), Nanchang University, Nanchang 330006, Jiangxi Province, China
Author contributions: Zhang L and Yan HF designed the research and wrote the first manuscript; Zhang L and Yan HF contributed to conceiving the research and analyzing data; Zhang L and Yan HF conducted the analysis and provided guidance for the research; All authors reviewed and approved the final manuscript.
Supported by Jiangxi Provincial Department of Education Science and Technology Research Project - Youth Project (Research on the application of high-pressure PICC catheter in abdominal CT enhancement of tumor patients), No. 200242.
Institutional review board statement: This study was approved by the Ethic Committee of The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Approval No. 0-Medical Research and Ethics Review (2024) No. 60.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hui-Feng Yan, BMed, Doctor, Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College (Jiangxi Provincial Key Laboratory of Intelligent Medical Imaging), Nanchang University, No. 1 Minde Road, Nanchang 330006, Jiangxi Province, China. 15879129481@163.com
Received: July 23, 2024
Revised: September 3, 2024
Accepted: October 8, 2024
Published online: December 15, 2024
Processing time: 117 Days and 15.4 Hours
Abstract
BACKGROUND

Individuals with diabetes mellitus have a higher risk of developing malignant tumors, and diagnosing these tumors can be challenging.

AIM

To confirm the benefits of using peripherally inserted central catheters (PICCs) in contrast-enhanced computerized tomography (CECT) for diagnostic imaging in diabetic patients with malignant tumors and to provide a research basis for follow-up research.

METHODS

This retrospective study analyzed 204 diabetic patients with malignancies treated at The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, from January 2024 to June 2024. The patients were divided into two groups: A control group (n = 102) with indwelling peripheral intravenous catheters and a research group (n = 102) with high-pressure-resistant PICC. The study compared baseline data, the incidence of iodine contrast extravasation during CECT, the incidence of adverse events (discomfort, redness and swelling at the puncture site, and blood oozing), imaging quality, nursing time, intubation success rate, number of venipuncture attempts, and catheter maintenance cost.

RESULTS

Male patients accounted for 51.96% in the control group and 55.88% in the research group; the average age was (59.68 ± 11.82) years in the control group and (61.41 ± 12.92) years in the research group; the proportions of lung cancer, colorectal cancer, and gastric cancer patients in the control group were 42.16%, 38.24%, and 19.61%, respectively, while those in the research group were 34.31%, 37.25%, and 28.43%, respectively. Except for the gender distribution, age, and cancer type mentioned above, other general information such as underlying diseases, puncture location, and long-term chemotherapy shows no significant differences as tested (P > 0.05). The results showed that the research group had significantly reduced incidence of iodine contrast extravasation (7 vs 1, P = 0.031), similar incidence of adverse events (11 vs 7, P = 0.324), reduced nursing time [(18.50 ± 2.68) minutes vs (13.26 ± 3.00) minutes, P = 0.000], fewer venipuncture attempts [(2.21 ± 0.78) times vs (1.49 ± 0.58) times, P = 0.000], lower catheter maintenance cost [(1251.79 ± 205.47) China yuan (CNY) vs (1019.25 ± 117.28) CNY, P = 0.000], increased intubation success rate (16.67% vs 58.82%, P = 0.000), and better imaging quality (85.29% vs 94.12%, P = 0.038).

CONCLUSION

High-pressure-resistant PICCs can lessen the physical burden of diabetic patients during nursing, reduce treatment costs, and improve the efficiency and quality of imaging for diagnosis malignant tumors.

Keywords: Diabetes mellitus complicated with malignant tumors; Contrast-enhanced computerized tomography; High-pressure-resistant peripherally inserted central catheters; The incidence of adverse events; Quality of computer tomography imaging

Core Tip: For patients with diabetes mellitus complicated by malignant tumors, there is potential for improving the administration of intravenous contrast agents during contrast-enhanced computerized tomography (CECT). High-pressure-resistant peripherally inserted central catheters (PICCs) may be a better option for this improvement. This study has demonstrated the advantages of using high-pressure-resistant PICC in CECT for such patients, including reducing the physical burden during nursing, lowering treatment costs, and enhancing the efficiency and quality of imaging. These novel findings offer a strong research foundation for future research.