Luo JY, Chen LG, Yan M, Mei YJ, Cui YQ, Jiang M. Effect of individualized nutrition interventions on clinical outcomes of pregnant women with gestational diabetes mellitus. World J Diabetes 2023; 14(10): 1524-1531 [PMID: 37970125 DOI: 10.4239/wjd.v14.i10.1524]
Corresponding Author of This Article
Min Jiang, PhD, Doctor, Clinical Medical College, Yangzhou University, No. 98, Nantong West Road, Yangzhou 225009, Jiangsu Province, China. jiangmin871101@163.com
Research Domain of This Article
Obstetrics & Gynecology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Oct 15, 2023; 14(10): 1524-1531 Published online Oct 15, 2023. doi: 10.4239/wjd.v14.i10.1524
Effect of individualized nutrition interventions on clinical outcomes of pregnant women with gestational diabetes mellitus
Jian-Ying Luo, Lang-Gui Chen, Mei Yan, Yue-Jing Mei, Ya-Qian Cui, Min Jiang
Jian-Ying Luo, Department of Clinical Nutrition, Northern Jiangsu People's Hospital of Jiangsu Province, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China
Jian-Ying Luo, Lang-Gui Chen, Yue-Jing Mei, Ya-Qian Cui, Min Jiang, Clinical Medical College, Yangzhou University, Yangzhou 225009, Jiangsu Province, China
Mei Yan, Clinical Medical College, Dalian Medical University, Dalian 116000, Liaoning Province, China
Min Jiang, Department of Gynaecology and Obstetrics, Northern Jiangsu People's Hospital of Jiangsu Province, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China
Author contributions: Luo JY and Chen LG contributed equally to this work; Luo JY and Chen LG designed the research study; Yan M, Mei YJ, Cui YQ and Jiang M contributed reagents and analytic tools; Luo JY, Chen LG and Jiang M analyzed the data; Luo JY and Chen LG wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Medical Ethics Committee of Northern Jiangsu People's Hospital of Jiangsu Province (Approval No. 2023ky150).
Informed consent statement: This is a retrospective study, and since the analysis used anonymous clinical data approved by the Ethics Committee of Northern Jiangsu People's Hospital of Jiangsu Province, the need for informed consent from subjects or guardians was waived.
Conflict-of-interest statement: The authors declare no competing interests.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min Jiang, PhD, Doctor, Clinical Medical College, Yangzhou University, No. 98, Nantong West Road, Yangzhou 225009, Jiangsu Province, China. jiangmin871101@163.com
Received: July 4, 2023 Peer-review started: July 4, 2023 First decision: July 19, 2023 Revised: August 17, 2023 Accepted: September 8, 2023 Article in press: September 8, 2023 Published online: October 15, 2023 Processing time: 97 Days and 1.3 Hours
Abstract
BACKGROUND
Gestational diabetes mellitus (GDM) can lead to excessive pregnancy weight gain (PWG), abnormal glucolipid metabolism, and delayed lactation. Therefore, it is necessary to provide appropriate and effective interventions for pregnant women with GDM.
AIM
To clarify the effects of individualized nutrition interventions on PWG, glucolipid metabolism, and lactation in pregnant women with GDM.
METHODS
The study population consisted of 410 pregnant women with GDM who received treatment at the Northern Jiangsu People's Hospital of Jiangsu Province and Yangzhou Maternal and Child Health Hospital between December 2020 and December 2022, including 200 who received routine in-terventions [control (Con) group] and 210 who received individualized nutrition interventions [research (Res) group]. Data on PWG, glucolipid metabolism [total cholesterol, (TC); triglycerides (TGs); fasting blood glucose (FPG); glycosylated hemoglobin (HbA1c)], lactation time, perinatal complications (cesarean section, premature rupture of membranes, postpartum hemorrhage, and pregnancy-induced hypertension), and neonatal adverse events (premature infants, fetal macrosomia, hypo-glycemia, and respiratory distress syndrome) were collected for comparative analysis.
RESULTS
The data revealed markedly lower PWG in the Res group vs the Con group, as well as markedly reduced TG, TC, FPG and HbA1c levels after the intervention that were lower than those in the Con group. In addition, obviously earlier lactation and statistically lower incidences of perinatal complications and neonatal adverse events were observed in the Res group.
CONCLUSION
Individualized nutrition interventions can reduce PWG in pregnant women with GDM, improve their glucolipid metabolism, and promote early lactation, which deserves clinical promotion.
Core Tip: Gestational diabetes mellitus (GDM) will increase the risk of perinatal complications and neonatal adverse events. This study mainly analyzed the clinical application of individualized nutrition interventions in pregnant women with GDM from the perspective of pregnancy weight gain, glycolipid metabolism, lactation time, perinatal complications, and neonatal adverse events, aiming to provide an optimal choice for the pregnancy management of pregnant women with GDM.
