Scientometrics
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2022; 13(9): 786-798
Published online Sep 15, 2022. doi: 10.4239/wjd.v13.i9.786
Mapping the global research landscape on insulin resistance: Visualization and bibliometric analysis
Sa’ed H Zyoud, Muna Shakhshir, Amer Koni, Amani S Abushanab, Moyad Shahwan, Ammar Abdulrahman Jairoun, Rand Al Subu, Adham Abu Taha, Samah W Al-Jabi
Sa’ed H Zyoud, Amer Koni, Amani S Abushanab, Samah W Al-Jabi, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa’ed H Zyoud, Poison Control and Drug Information Center, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Sa’ed H Zyoud, Clinical Research Centre, An-Najah National University Hospital, Nablus 44839, Palestine
Muna Shakhshir, Department of Nutrition, An-Najah National University Hospital, Nablus 44839, Palestine
Amer Koni, Division of Clinical Pharmacy, Department of Hematology and Oncology Ph-armacy, An-Najah National University Hospital, Nablus 44839, Palestine
Moyad Shahwan, Department of Pharmacy, Ajman University, Ajman 346, United Arab Emirates
Moyad Shahwan, Centre of Medical and Bio Allied Health Sciences Research, Ajman University, Ajman 346, United Arab Emirates
Ammar Abdulrahman Jairoun, Department of Health and Safety, Dubai Municipality, Dubai 67, United Arab Emirates
Rand Al Subu, Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Adham Abu Taha, Department of Biomedical Sciences, College of Medicine and Health Sciences, An-Najah National University, Nablus 44839, Palestine
Adham Abu Taha, Department of Pathology, An-Najah National University Hospital, Nablus 44839, Palestine
Author contributions: Zyoud SH developed the concept for the manuscript, reviewed the literature, designed the study, collected the data, analyzed the data, made significant contributions to the existing literature search and interpretation of the manuscript, and wrote the manuscript; Shakhshir M, Koni A, Abushanab AS, Jairoun AA, Shahwan WM, Al Subu R, Abu Taha A, and Al-Jabi SW participated in interpretation of the data and made revisions to the initial draft; and all authors provided critical review and approved the final manuscript before submission.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sa’ed H Zyoud, PhD, Associate Professor, Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Academic Street, Nablus 44839, Palestine. saedzyoud@yahoo.com
Received: March 3, 2022
Peer-review started: March 3, 2022
First decision: April 17, 2022
Revised: May 4, 2022
Accepted: August 5, 2022
Article in press: August 5, 2022
Published online: September 15, 2022
Abstract
BACKGROUND

Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses, including obesity, type 2 diabetes, and cardiovascular disease.

AIM

To investigate and map global insulin resistance studies.

METHODS

A bibliometric methodology was applied to the literature retrieved from the Scopus database and Reference Citation Analysis (https://www.referencecitationanalysis.com) by using a validated search strategy. The study period was limited from 2002 to 2021. Bibliometric indicators and mapping were presented.

RESULTS

A total of 26808 articles on the topic of insulin resistance were included in the Scopus database. The articles included research articles (n = 21918; 81.76%), review articles (n = 2641; 9.85%), and letters (n = 653; 2.44%). During the study period, 136 countries contributed to the research on insulin resistance. The highest number of articles was from the United States (n = 7360; 27.45%), followed by China (n = 3713; 13.85%), Japan (n = 1730, 6.45%), Italy (n = 1545; 5.54%), and the United Kingdom (n = 1484; 5.54%). The retrieved articles identified two main research themes: “inflammatory mechanisms in the regulation of insulin resistance” and “mechanisms linking obesity to insulin resistance”.

CONCLUSION

Our data show that insulin resistance has steadily gained interest from researchers, as evidenced by the number of citations and yearly publications. Publications have grown significantly in the last decade, while low-income countries with greater burdens continue to produce fewer publications in this field. This approach might assist researchers in choosing new research areas and recognizing research hotspots and frontiers. In the future, perhaps high-quality clinical evidence will be acquired.

Keywords: Insulin resistance, Research hotspots, Scopus, VOSviewer, Bibliometric

Core Tip: Several bibliometric studies have been conducted in the field of diabetes research. However, no bibliometric study has been conducted on insulin resistance research. Therefore, the current study aims to investigate and map global research on insulin resistance. The retrieved articles identified two main research themes: “inflammatory mechanisms in the regulation of insulin resistance” and “mechanisms linking obesity to insulin resistance”. This approach might assist researchers in choosing new research areas and recognizing research hotspots and frontiers. In the future, perhaps high-quality clinical evidence will be acquired.