• Hypertension
• Knowledge
• Self-care practice

• Ethiopia
• North Shewa
• hypertension
• public hospitals
• self-care practices

• Case–control
• Determinant
• Ethiopia
• Guji
• Uncontrolled blood pressure

• Humans
• Ethiopia/epidemiology
• Hypertension/drug therapy
• Hypertension/epidemiology
• Male
• Female
• Case-Control Studies
• Middle Aged
• Adult
• Hospitals, General
• Follow-Up Studies
• Risk Factors
• Aged

• Guraghe zone
• Hypertension
• Self-care adherence

• Hypertension
• control level
• practice
• self-care behaviour
• urban slum population

• Humans
• Hypertension/epidemiology
• Male
• Female
• Poverty Areas
• India/epidemiology
• Middle Aged
• Self Care
• Adult
• Cross-Sectional Studies
• Surveys and Questionnaires
• Risk Factors
• Health Knowledge, Attitudes, Practice
• Urban Population/statistics & numerical data
• Aged
• Socioeconomic Factors

• Alzheimer’s disease
• clinical biomarkers
• elderly population
• hypertension

• Aged
• Humans
• Alzheimer Disease/psychology
• Brain/pathology
• Hypertension
• Cognitive Dysfunction/psychology
• Blood Pressure

• Postgraduate Education Reform and Quality Improvement Project of Henan Province
• Postgraduate Cultivating Innovation and Quality Improvement Action Plan of Henan University
• Henan Provincial Science and Technology Research Project

• Bale Zone
• Blood pressure control
• Hypertension
• Self-care

Hypertension (HTN) and type 2 diabetes mellitus (T2DM) are often coincident, and each condition is considered a risk factor for the other. Both occur frequently in the Inner Mongolia region of China. The reasons for differences in risk between Han and Mongolian ethnic groups are not known. The LEPR gene and its polymorphism, rs1137101 (Gln223Arg), are both considered risk factors for HTN and T2DM, but any role of rs1137101 in the occurrence of HTN + T2DM remains unclear for Mongolian and Han populations in the Inner Mongolia region.

To investigate the relationship between rs1137101 and the occurrence of HTN with T2DM in Mongolian and Han populations in Inner Mongolia.

A total of 2652 subjects of Han and Mongolian ethnic origins were enrolled in the current study, including 908 healthy controls, 1061 HTN patients and 683 HTN patients with T2DM.

The association between the rs1137101 polymorphism and HTN with T2DM was analyzed, and differences between Han and Mongolian individuals assessed. There was a significant correlation between rs1137101 and HTN (co-dominant, dominant, over-dominant and log-additive models) and HTN + T2DM (co-dominant, dominant, over-dominant and log-additive models) after adjustment for sex and age in individuals of Mongolian origin. rs1137101 was significantly associated with HTN (co-dominant, recessive and log-additive models) and HTN + T2DM (co-dominant, dominant, over-dominant and log-additive models) in the Han Chinese population.

Mongolian and Han subjects from Inner Mongolia with HTN who had rs1137101 were protected against the development of T2DM. Allele A has the opposite impact on the occurrence of HTN in Mongolian and Han Chinese populations.

• rs1137101
• Mongolian
• Han Chinese
• Hypertension
• Type 2 diabetes mellitus
• Associate study

Hypertension is a silent killer that causes serious health issues in all parts of the world. Hypertension is a risk factor for cardiovascular disease, stroke, and kidney disease. Self-care practices have been identified as an important component of hypertension management. Despite the government's commitment and the interventions of various stakeholders, the burden of hypertension and its sequel remain unabated. A recent study showed that hypertension self-care practices play a vital role in controlling and managing high blood pressure, even though there is poor self-practice among hypertensive patients in Ethiopia. Therefore, this study assessed the level of self-care practices and associated factors among hypertension patients in public hospitals in Harari regional state and Dire Dawa City Administration, Eastern Ethiopia.

Hospital-based cross-sectional study was conducted from June 15 to July 15/2021 among 415 adult hypertensive patients on follow-up. The participants were selected using systematic sampling. Hypertension Self-Care Activity Level Effects (H-SCALE) was used to collect data through face-to-face interviews. The SPSS version 24 was used for analysis. Logistic regression analyses were done to determine the association between the outcome and independent variables. For multivariate logistic regression models, variables having a P < 0.25 during bivariate analysis were candidates. The strength of the association was estimated using AOR and 95% CI. The level of statistical significance was declared at a p < 0.05.

This study revealed that 52% (95% CI, 48.2–58%) had good level of self-care practices. Formal education (AOR = 3.45, 95% CI: 2.1–4.85), good knowledge about hypertension (AOR = 1.5, 95% CI: 1.17–2.1) 1.5, abstain from chewing khat (AOR = 2.01, 95% CI: 1.44–3.94), strong social support (AOR= 1.9, 95% CI: 1.16–3.1), and absence of depression (AOR = 2.03, 95% CI: 1.43–3.92) were statistically associated with a good level of self-care practices.

This study pointed out that about half of the participants had a good level of self-care practices. Formal education, good knowledge about hypertension, abstaining from khat chewing, good social support, and absence of depression showed associations with a good level of self-care practices. Therefore, public health interventions on hypertension self-care practices, and strengthening non-communicable diseases control programs are vital. Moreover, the provision of targeted education to patients can improve disease knowledge and self-care practices.

• Adult
• Cross-Sectional Studies
• Ethiopia/epidemiology
• Hospitals, Public
• Humans
• Hypertension/epidemiology
• Self Care