Critical evaluation of contemporary management in a new Pelvic Exenteration Unit: The first 25 consecutive cases

Table 1 Characteristics of patients who underwent pelvic exenteration

Variable
Sex, n (%)
Male	16 (64)
Female	9 (36)
Age, n (%)	Median, 61.9 yr (range, 30-72)
ASA score, n (%)	I: 11 (44)
	II: 13 (52)
	III: 1 (4)
	Median, 2
ECOG status	0: 22 (88)
	1: 2 (8)
	3: 1 (4)
	Median, 0
Co-morbidities, n (%)
Hypertension	6 (24)
Diabetes mellitus	5 (20)
Hyperlipidaemia	8 (32)
Ischaemic heart disease	1 (4)
Primary cancer type (n = 16)
Colorectal	12
Chordoma	3
Gynaecological	1
Recurrent cancer type (n = 9)
Colorectal	6
Gynaecological	3

ASA: American Society of Anesthesiologists; ECOG: Eastern Cooperative Oncology Group.

Table 2 Pre-operative and operative treatment details

Incidence of neoadjuvant chemoradiation
Primary cancer
Colorectal	75%
Chordoma	0%
Gynaecological	0%
Recurrent cancer
Colorectal	67%
Gynaecological	0%
Operative procedure, n (%)
Total PE	1 (4)
Total PE with lateral exenteration	9 (36)
Anterior PE	3 (12)
Anterior and Lateral PE	1 (4)
Posterior PE	2 (8)
Posterior and Lateral PE	5 (20)
Lateral PE	4 (16)
Sacrectomy combined with any above PE procedures	9 (36)

PE: Pelvic exenteration.

Table 3 Clavien-Dindo classification of surgical complications, n = 12

Grade	Feature	n
2	Wound infection	6
	Urinary tract infection	4
	Venous access infection	4
	Prolonged ileus	1
	Deep vein thrombosis	1
	Acute myocardial infarction	1
3	Postoperative bleeding: Re-laparotomy	1
	Donor site-infected seroma percutaneous drainage	1
4	Temporary renal dialysis	1
Total adverse events		20

Table 4 Characteristics of post-pelvic exenteration recurrent diseases

Pre-PE status	Histology origin	Regional recurrence	Distant metastasis	Regional and distant	R0	R1
Primary	Colonic	0	0	1	1	0
Primary	Rectal	0	1	1	0	2
Primary	Sacral chordoma	1	0	0	1	0
Recurrent	Rectal	1	0	0	0	1
Recurrent	Cervical	0	1	1	2	0
Total		2	2	3	4	3

Both microscopic resection margin status and pre-exenteration primary or recurrent tumours do not show any statistically significant influence on post-exenteration recurrence (P = 0.67). PE: Pelvic Exenteration.