Copyright ©The Author(s) 2017.
World J Gastrointest Oncol. Feb 15, 2017; 9(2): 50-61
Published online Feb 15, 2017. doi: 10.4251/wjgo.v9.i2.50
Table 1 Unification of terms relating to anal intraepithelial neoplasia
Condyloma or ASCUSAIN grade IAIN grade IIAIN grade III
Mild dysplasiaModerate dysplasiaSevere dysplasia
Table 2 Rates of anal cancer among various populations compiled from various sources
Anal cancer rates among select populations, per 100000 person-years
General population2[1]
General population, female0.55-2.4[13]
HIV positive women3.9-30[13]
HIV negative MSM5.1[12]
Solid organ transplant10-15[66]
Prior HPV related malignancy0.8-63.8[13]
HIV positive MSM49.5[12]
Colon cancer in general population41[2]
Table 3 Progression rates of anal intraepithelial neoplasia to squamous cell carcinoma
ProgressionNo. patientsRate of progressionMedian or average progression timeRef.
AIN II/III to SCC7211%42 mo[33]
AIN III to SCC358.6%53 mo[34]
AIN I to AIN III19912.6% (8.1/100 person-years)18 mo[35]
ASCUS/AIN I to AIN II/III55624.5% (10.5/100 person-years)36 mo[36]
HSIL to SCC13819.6%57 mo. w/prevalent HSIL; 64 mo. w/incident HSIL[37]