Otsuka Y, Akahoshi K, Yasunaga K, Kubokawa M, Gibo J, Osada S, Tokumaru K, Miyamoto K, Sato T, Shiratsuchi Y, Oya M, Koga H, Ihara E, Nakamura K. Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer. World J Gastrointest Oncol 2017; 9(10): 416-422 [PMID: 29085568 DOI: 10.4251/wjgo.v9.i10.416]
Corresponding Author of This Article
Kazuya Akahoshi, MD, PhD, Department of Gastroenterology, Aso Iizuka Hospital, 3-83 Yoshio, Iizuka 820-8505, Japan. kakahoshi2@aol.com
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Oct 15, 2017; 9(10): 416-422 Published online Oct 15, 2017. doi: 10.4251/wjgo.v9.i10.416
Table 1 Patient characteristics n (%)
Older group (n = 64)
Non-older group (n = 168)
P value
Mean age
84.2
69.5
Gender ratio (M/F)
44/20
118/50
NS
No. of performance state 3 or 4
5 (7.8)
4 (2.4)
Pre-existing comorbidity
Total prevalence rates
58 (90.6)
123 (73.2)
0.0042
Cerebral infarction
11 (17.2)
17 (10.1)
NS
Cardiovascular disease
23 (35.9)
25 (14.9)
0.0004
Respiratory disease
8 (12.5)
12 (7.1)
NS
Chronic renal dysfunction
8 (12.5)
21 (12.5)
NS
Liver cirrhosis
1 (1.6)
12 (7.1)
NS
Diabetes
20 (31.2)
47 (28.0)
NS
Hypertension
44 (68.8)
98 (58.3)
NS
Senile dementia
7 (10.9)
14 (8.3)
NS
Anti-coagulant therapy
4 (6.3)
12 (7.1)
NS
Table 2 Tumors characteristics
Older group (n = 64)
Non-older group (n = 168)
P value
Location
Upper
28
39
0.019
Middle
16
55
NS
Lower
20
72
NS
Residual stomach
0
2
Mean tumor size
17.5
15.6
NS
Histological type
Well differentiated
58
149
NS
Moderately differentiated
5
10
NS
Poorly differentiated
0
8
NS
Papillary differentiated
1
1
NS
Category of indication
Guideline lesion
47
118
NS
Lesion included in the expanded indications
17
50
NS
Table 3 Technical outcome n (%)
Older group (n = 64)
Non-older group (n = 168)
P value
En bloc resection
63 (98.4)
168 (100)
NS
R0 resection
61 (95.3)
168 (100)
0.03
Complications
Intraoperative hemorrhage
0 (0)
0 (0)
NS
Intraoperative perforation
1 (1.6)
0 (0)
NS
Postoperative hemorrhage
1 (1.6)
8 (4.8)
NS
Postoperative perforation
0 (0)
0 (0)
NS
Table 4 Social and economic outcomes n (%)
Parameter
Older group (n = 64)
Non-older group (n = 168)
P value
Worsening of the performance status
3/64 (4.7)
1/168 (0.6)
NS
Mean duration of hospitalization (d)
11.4
10.7
NS
Mean financial cost of admission (JPY)
657040
574890
NS
Citation: Otsuka Y, Akahoshi K, Yasunaga K, Kubokawa M, Gibo J, Osada S, Tokumaru K, Miyamoto K, Sato T, Shiratsuchi Y, Oya M, Koga H, Ihara E, Nakamura K. Clinical outcomes of Clutch Cutter endoscopic submucosal dissection for older patients with early gastric cancer. World J Gastrointest Oncol 2017; 9(10): 416-422