Greater omentum gastrointestinal stromal tumor with PDGFRA-mutation and hemoperitoneum

Table 1 Polymerase chain reaction primers used to analyze c-kit and PDGFRA gene exons

Gene	Exon	Forward primer	Reverse primer
c-kit	9	TTCCCTTTAGATGCTCTGCTTCT	CCTTTGTTGTTACCTTTAAATGC
	11	GAGTGCTCTAATGACTGAGA	AAAGGTGACATGGAAAGCCC
	13	GCTTGACATCAGTTTGCCAG	AAAGGCAGCTTGGACACGGCTTTA
	17	GTTTTCTTTTCTCCTCCAAC	TGCAGGACTGTCAAGCAGAG
PDGFRA	12	GGACTTTGGTAATTCACCAG	TGTAAAGTTGTGTGCAAGGG
	14	ACAGGAAGTTGGTAGCTCAG	TCACAACCACATGTGTCCAG
	18	ACCATGGATCAGCCAGTCTT	TGAAGGAGGATGAGCCTGACC

Table 2 Clinicopathologic findings in 11 cases of omental gastrointestinal stromal tumor

Case No.	Age (yr)/sex	Size (cm)	Mitosis/50HPF	Risk group	Cell type	Mutation	Follow up (mo)	Outcome	Ref.
1	73/F	4	31	Low	Myxoid Ep	Exon18 del D842V	4	NED	[5]
2	52/M	> 20	41	High	Ep	Exon18 D842_H845del	13	NED	[5]
3	49/F	17	1	3b	Ep	Exon18 D842_H845del	48	NED	[12]
4	65/M	20	2	3b	Myxoid Ep	Exon12 V561D	6	NED	[20]
5	64/M	15	115	6b	Sp	Exon12 polymorphism Q567P	NA	NED	[21]
6	62/F	11	3	3b	Ep	Exon 18 D842V	87	NED	[22]
7	41/M	19	0	3b	Ep	Exon 18 D842V	27	NED	[22]
8	69/M	8.5	1	3a	Ep	Exon18 del IMHD843-846	20	NED	[22]
9	54/F	20	18	6b	Ep	Exon 18 del DIMH842-845	15	DOD	[22]
10	59/M	33	1	3b	Ep	Exon 18 D842Y	2	DOD	[22]
11	43/M	19	6	6b	Ep	Exon18 D846E, N848K	24	NED	Our case

¹MIB-1-labeling index (%). Tumors were divided into risk groups described previously[18,22]. Case 1 and 2 were graded as high, intermediate, or low risk as described previously[22]. Ep: Epithelioid; Sp: Spindle; NED: No evidence of disease; DOD: Die of disease; NA: Not available.