Clinical outcomes of gastrointestinal stromal tumor in southern Thailand

Table 1 Resectability of gastrointestinal stromal tumor according to primary tumor sites n (%)

Primary sites	No. of cases	Complete resection	Residual disease	Unresectable
Stomach	43	30 (70)	9 (20)	4 (9)
Small bowel	33	20 (61)	6 (18)	7 (21)
Rectum	5	2 (40)	1 (20)	2 (40)
Extra-gastrointestinal	18	4 (22)	5 (28)	9 (50)

Table 2 Response to targeted therapy according to site of primary tumor n (%)

	PR1	SD	PD
All 47 cases	7 (15)	27 (57)2	13 (28)
Stomach (13 cases)	4 (31)	7 (54)	2 (15)
Small bowel (19 cases)	1 (5)	10 (53)	8 (42)
Rectum (2 cases)	-	2 (100)	-
Extra-gastrointestinal (13 cases)	2 (15)	8 (62)	3 (23)

¹Response as evaluated by the response evaluation criteria in solid tumors method;

²One case in this group had complete histopathological response. SD: Stable disease; PD: Progressive disease; PR: Partial response.

Table 3 Univariate survival analysis of factors associated with survival in 99 cases of gastrointestinal stromal tumors

	Four-year OS (%)	P value
OS (99 cases)	72.4
Primary tumor site		0.02
Stomach	86.5
Non-stomach	64.5
Risk category1		< 0.01
Non-high risk (35 cases)	92
High risk (64 cases)	60.9
Liver metastasis at diagnosis		< 0.01
Absent (72 cases)	86.3
Present (27 cases)	44.6
Residual disease after surgery		0.04
Absent (56 cases)	84.1
Present (21 cases)	61.5
Response to targeted therapy		0.03
CR + PR (8 cases)	88.9
SD + PD (40 cases)	64.2

¹Risk categorization according to the United States National Institute of Health consensus 2002. OS: Overall survival; SD: Stable disease; PD: Progressive disease; CR: Complete response; PR: Partial response.