Emerging role of vitamin D in colorectal cancer

Table 1 Anti-cancer effects of vitamin D in various rodent models

Treatment	Inducer	Species	Results	Ref.
Supplement		VDR knockout mouse	Inhibition of hyperproliferation and adenoma formation	[24]
Supplement		Apc1638 mice	Inhibition of carcinoma incidence	[25]
Deficiency		Balb/C mice	Enhancement of cancer cell growth	[26]
Supplement		Balb/C mice	Inhibition of tumor growth	[27]
Supplement		C57BL/6J mice	Inhibition of hyperproliferation	[28]
			Inhibition of tumor incidence
Deficiency	DMH	SD rat	No effect	[29]
Deficiency		SD rat	Enhancement of carcinogenesis	[30]
Supplement	DMH	Fisher344 rat	No effect	[31]
Supplement	DMH	Fisher344 rat	Inhibition of tumor incidence	[32]