Peroxisome proliferator activated receptor-γ and the ubiquitin-proteasome system in colorectal cancer

Table 1 PPARγ regulation by the ubiquitin-proteasome system

Degradation of PPARγ itself

Degradation of co-activators

Degradation of inhibiting kinases

Regulation of antagonistic transcription factors (β-catenin, NF-κB)

Degradation of calcineurin inhibitor DSCR1 (RCAN1)

PPARγ: Peroxisome proliferator activated receptor-γ.