New insights on cholangiocarcinoma

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Mar 15, 2010 (publication date) through May 3, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Mar 15, 2010; 2(3): 136-145
Published online Mar 15, 2010. doi: 10.4251/wjgo.v2.i3.136

Table 1 Recently proposed serum and bile biomarkers for the diagnosis of Cholangiocarcinoma

Biomarker	Sensitivity (%)	Specificity (%)
Serum
CA19-9	53-92	50-98
CEA	33-68	79-100
IL-6	73	92
Trypsinogen-2	AUC = 0.804
MUC5AC	71.01	90
CYFRA 21-1	74.7	92.2
Bile
CA19-9	46-61	60-70
CEA	67-84	33-80
IGF1	100	100
Pancreatic elastase/amylase ratio	82	89
Mcm5	62	67

CEA: Carcinoembryonic antigen; IL-6: Interleukin-6; IGF1: Insulin like growth factor 1

Citation: Gatto M, Alvaro D. New insights on cholangiocarcinoma. World J Gastrointest Oncol 2010; 2(3): 136-145
URL: https://www.wjgnet.com/1948-5204/full/v2/i3/136.htm
DOI: https://dx.doi.org/10.4251/wjgo.v2.i3.136