Ultrasound diagnosis of small bowel adenocarcinoma in Crohn’s disease: A case report and review of literature

Table 1 Demographic and clinical characteristics

Characteristics		n = 82	mean ± SD/percentage (%)
Age(years)		81	41.8 ± 13.2
	ND	1
Duration of Crohn’s disease (years)		72	19.3 ± 11.1
	ND	10
Gender	Male	57	69.51
	Female	25	30.49
History of prior intestinal surgery	Yes	39	47.56
	No	43	52.44
History of prior IBD therapy	Corticosteroids	45	58.44
	Aminosalicylate	39	50.65
	Immunomodulators	35	45.45
	Anti-TNF	21	27.27
	Antibiotics	1	1.29
	ND	5
Symptom	Abdominal pain	56	88.89
	Diarrhea	27	42.86
	Nausea and vomiting	29	46.03
	Anemia	21	33.33
	Hematochezia	10	15.87
	Weight loss	28	44.44
	Fever	2	3.17
	Abdominal mass	2	3.17
	ND	19
Location	Terminal ileum	34	44.74
	Ileum	32	42.10
	Jejunum	7	9.21
	Mid-small bowel	3	3.95
	ND	6
Colonoscopy	Indication of tumor	5	38.46
	No indication of tumor	8	61.54
	ND	69
Tumor marker (CEA, CA19-9)	Elevated	4	28.57
	Normal	10	71.43
	ND	68
Differentiation degree	Low differentiation	11	45.83
	Moderate-low differentiation	1	4.17
	Moderate differentiation	6	25
	High differentiation	6	25
	ND	58
T classification	Tis	1	2.33
	1	1	2.33
	2	3	6.98
	3	15	34.88
	4	23	53.48
	ND	39
N classification	Yes	26	60.47
	No	17	39.53
	ND	39
M classification	Yes	9	18.75
	No	39	81.25
	ND	34

ND: Not described; IBD: Inflammatory bowel diseases; TNF: Tumor necrosis factor; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9.

Table 2 Radiological features

Characteristics		n = 61	Percentage (%)
Bowel wall thickening	Yes	51	83.61
	No	10	16.39
Focal loss of mural stratification	Yes	17	35.42
	No	31	64.58
	ND	13
Adjacent fat stranding	Yes	14	33.33
	No	28	66.67
	ND	19
Bowel obstruction	Yes	34	55.74
	No	27	44.26
Stricturing disease	Yes	31	73.81
	No	11	26.19
	ND	19
Lymphadenopathy	Yes	28	45.90
	No	33	54.10
Other evidence of distant spread (liver metastases, peritoneal metastasis, etc.)	Yes	9	14.75
	No	52	85.25
Penetrating disease (including fistula, abscess and perforation)	Yes	18	29.51
	No	43	70.49
Malignancy suggesting	Yes	17	27.87
	No	44	72.13

ND: Not described.