Techniques, perioperative outcomes, prognosis, and survival associated with laparoscopic surgery for T3-T4a colon cancer

Table 1 Comparison of perioperative indicators in the two groups, n = 101, mean ± SD

Group	Operation time, minutes	Intraoperative blood loss, mL	Number of lymph nodes cleared, count	Drainage time, days	Time to first flatus, days	Hospital stay, days
Open	201.02 ± 9.24	310.10 ± 10.57	14.11 ± 1.16	9.70 ± 2.33	4.81 ± 1.07	11.44 ± 2.67
Laparoscopic	208.21 ± 10.43	299.22 ± 8.48	16.23 ± 2.27	8.02 ± 1.79	3.98 ± 0.93	11.31 ± 2.43
t	5.186	8.069	8.358	5.746	5.884	0.362
P value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	0.718

Table 2 Comparison of complication rates in the two patient groups, n = 101, n (%)

Group	Wound infection	Pelvic infection	Iliac passion	Anastomotic fistula	Total incidence
Open	16 (34.78)	19 (41.30)	9 (8.91)	2 (1.98)	46 (45.54)
Laparoscopic	12 (26.09)	13 (12.87)	6 (5.94)	1 (0.99)	32 (31.68)
χ2					4.093
P value					0.043

Table 3 Comparison of prognosis and survival during the follow-up period in the two groups, n = 101, n (%)

Group	1-year DFS	3-year DFS	1-year OS	3-year OS
Open	90 (89.19)	66 (65.35)	92 (91.09)	79 (78.22)
Laparoscopic	93 (92.08)	71 (70.30)	96 (95.05)	83 (82.18)
χ2	0.522	0.567	1.227	0.499
P value	0.470	0.451	0.268	0.480

DFS: Disease-free survival; OS: Overall survival.

Table 4 Comparison of survival outcomes in the follow-up period of the left-sided colon subgroup of patients, n (%)

Group	1-year DFS	3-year DFS	1-year OS	3-year OS
Laparotomy (n = 58)	53 (91.37)	40 (68.97)	54 (93.10)	49 (84.48)
Laparoscopic (n = 61)	57 (93.44)	43 (70.49)	58 (95.08)	51 (83.61)
χ2	0.181	0.032	0.210	0.017
P value	0.670	0.856	0.647	0.896

DFS: Disease-free survival; OS: Overall survival.

Table 5 Comparison of survival in the follow-up period of the right-sided colon subgroup of patients, n (%)

Group	1-year DFS	3-year DFS	1-year OS	3-year OS
Open (n = 43)	37 (86.05)	26 (60.47)	38 (88.37)	30 (69.77)
Laparoscopic (n = 40)	36 (90.00)	28 (70.00)	38 (95.00)	32 (80.00)
χ2	0.306	0.829	1.179	1.148
P value	0.580	0.363	0.278	0.284

DFS: Disease-free survival; OS: Overall survival.

Table 6 Comparison of survival between the two groups of T4a patients during the follow-up period, n (%)

Group	1-year DFS	3-year DFS	1-year OS	3-year OS
Open (n = 45)	39 (86.67)	28 (62.22)	41 (91.11)	31 (68.89)
Laparoscopic (n = 49)	44 (89.80)	33 (67.35)	46 (93.88)	36 (73.47)
χ2	0.222	0.270	0.016	0.240
P value	0.637	0.603	0.900	0.624

DFS: Disease-free survival; OS: Overall survival.