Copyright
©The Author(s) 2025.
World J Gastrointest Oncol. Apr 15, 2025; 17(4): 102913
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.102913
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.102913
Table 1 The association between F-box protein 22 expression and clinicopathological characteristics, n (%)
Pathological trait | Number of cases | Expression of FBXO22 | χ2 | P value | |
High (n = 55) | Low (n = 18) | ||||
Age | 0.003 | 0.957 | |||
≥ 60 | 28 | 21 (38.18) | 7 (38.89) | ||
< 60 | 45 | 34 (61.82) | 11 (61.11) | ||
Gender | 0.125 | 0.724 | |||
Male | 42 | 31 (56.36) | 11 (61.11) | ||
Female | 31 | 24 (43.64) | 7 (38.89) | ||
BMI | 0.408 | 0.523 | |||
≥ 25 kg/m2 | 29 | 23 (41.82) | 6 (33.33) | ||
< 25 kg/m2 | 44 | 32 (58.18) | 12 (66.67) | ||
Educational background | 0.054 | 0.816 | |||
High school and above | 26 | 20 (36.36) | 6 (33.33) | ||
Junior high school and below | 47 | 35 (63.64) | 12 (66.67) | ||
Tumor stages | 6.508 | 0.011 | |||
I-II | 42 | 27 (49.09) | 15 (83.33) | ||
III-IV | 31 | 28 (50.91) | 3 (16.67) | ||
Lymph node metastasis | 10.392 | 0.001 | |||
Yes | 32 | 30 (54.55) | 2 (22.11) | ||
No | 41 | 25 (45.45) | 16 (88.89) | ||
Degree of differentiation | 5.890 | 0.015 | |||
Low | 30 | 27 (49.09) | 3 (16.67) | ||
Middle and high | 43 | 28 (50.91) | 15 (83.33) | ||
Diameter of the tumour | 6.334 | 0.012 | |||
≥ 3 cm | 35 | 31 (56.36) | 4 (22.22) | ||
< 3 cm | 38 | 24 (43.64) | 14 (77.78) | ||
Smoking history | 1.853 | 0.173 | |||
Yes | 50 | 40 (72.73) | 10 (55.56) | ||
No | 23 | 15 (27.27) | 8 (44.44) | ||
Drinking history | 0.003 | 0.957 | |||
Yes | 45 | 34 (61.82) | 11 (61.11) | ||
No | 28 | 21 (38.18) | 7 (38.89) |
- Citation: Lu XF, Zhang HW, Chang X, Guo YZ. F-box protein 22: A prognostic biomarker for colon cancer associated with immune infiltration and chemotherapy resistance. World J Gastrointest Oncol 2025; 17(4): 102913
- URL: https://www.wjgnet.com/1948-5204/full/v17/i4/102913.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i4.102913