Application of fecal immunochemical test in colorectal cancer screening: A community-based, cross-sectional study in average-risk individuals in Hainan

Table 1 Analysis of fecal immunochemical test results

	Number of examples (n = 1788)	FIT-positive (n = 79)	χ2	P value
Sex			121.386	0.000
Male	603	37
Female	1285	42
Age			6.966	0.008
41-50	667	19
51-60	504	25
61-70	397	17
≥ 71	225	19
Region			6.372	0.027
Haikou	443	45
Sanya	425	6
Dongfan	268	8
Qionghai	245	9
Wuzhishan	381	11
Total	1788	79

FIT: Fecal immunochemical test.

Table 2 Analysis of high-risk factors for positive fecal immunochemical test results

Factor	Number of examples (n = 1788)	FIT-positive (n = 79)	χ2	P value
Sleep quality			5.746	0.057
Better	543	17
So so	681	53
Difference	565	19
Anxiety/stress			4.833	0.089
Seldom	706	33
Occasionally	685	36
Often	399	20
Mental illness			20.021	0.000
No	1428	50
Yes	360	39
Level of education			1.712	0.425
Elementary school	292	15
Junior high school	825	39
College degree or above	168	5
Exercise time per week			4.054	0.032
< 1 hour	489	19
1-4 hours	513	30
> 4 hours	308	10
Eating regularly or not			2.655	0.103
Yes	1500	42
No	238	17
Smoking			20.789	0.000
No	1102	35
Yes	686	24
Drinking			17.869	0.000
No	922	26
Yes	387	33
Pickled foods			6.287	0.012
No	1434	36
Yes	354	23
Areca catechu			4.748	0.029
No	1571	44
Yes	217	15

FIT: Fecal immunochemical test.

Table 3 Analysis of high-risk factors for positive fecal immunochemical test results cases multiple logistic regression analysis

Factor	β	SEB	Wald χ2	P value	OR (95%CI)
Age	0.237	0.108	4.152	0.008	1.121 (0.097-1.453)
Pickled foods	0.583	0.251	4.382	0.012	1.421 (1.212-1.671)

OR: Odds ratio; CI: Confidence interval.

Table 4 Comparison of colonoscopy compliance among fecal immunochemical test-positive subjects

Factor	Total	FIT-positive	Colonoscopy cases	χ2	P value
Sex
Male	603	37	20	1.516	0.509
Female	1285	42	35	0.652	0.823
Age
41-50	667	19	13	1.907	0.167
51-60	504	25	20	4.523	0.033
61-70	397	17	10	0.719	0.396
≥ 71	225	19	12	9.817	0.000
Region
Haikou	443	45	20	5.715	0.017
Sanya	425	6	6	0.556	0.782
Dongfan	268	8	15	0.449	0.048
Qionghai	245	9	9	0.504	0.618
Wuzhishan	381	11	5	11.021	0.000
Total	1788	79	55

FIT: Fecal immunochemical test.

Table 5 Colonoscopy results of participants with fecal immunochemical test positive results

Colonoscopy results	Number of examples
Benign results
Hemorrhoids	6
Enteritis	4
Normal	5
Polyps or adenomas
Descending colonic tubular adenoma	6
Tubular adenoma of the transverse colon	7
Tubular adenoma of the sigmoid colon	7
Tubular adenoma of the ascending colon	6
Sigmoid inflammatory polyps	4
Sigmoid proliferative polyps	5
Advanced adenoma
Tubular adenoma of the sigmoid colon	3
Descending colonic tubular adenoma	1
Sigmoid villous adenoma	2
Sigmoid colon villous-tubular adenoma	1
Tubular adenoma of the transverse colon	1
CRC	2
Total	55

CRC: Colorectal cancer.