Causal effects of genetic birth weight and gestational age on adult esophageal diseases: Mendelian randomization study

Table 1 Genome-wide association study data sources and information included in the current study

Phenotype	Unit	Sample size	Ancestry	GWAS ID/data source	PMID
Educational attainment (years of education)	SD increase in years of education	461457	European	ebi-a-GCST90029013	29892013
Body mass index	SD increase in body mass index	681275	European	ieu-b-40	30124842
Height	SD increase in cm of height	458235	European	ebi-a-GCST90025949	34226706
Weight	SD increase in kg of birth adult weight	360116	European	ebi-a-GCST90018949	34594039
Major depressive disorder	Binary categorical variable	173005	European	ieu-a-1188	29700475
Cigarettes smoked per day	SD increase in cigarettes smoked per day	337334	European	ieu-b-25	30643251
Alcoholic drinks per week	SD increase in alcoholic drinks per week	335394	European	ieu-b-73	30643251
Birth weight	SD increase in kg of birth weight	143677	European	ieu-a-1083	27680694
Gestational duration	SD increase in days of gestational duration	84689	European	EGG Consortium	31477735
Early preterm birth	Binary categorical variable	38995	European	EGG Consortium	31477735
Preterm birth	Binary categorical variable	57153	European	EGG Consortium	31477735
Post term birth	Binary categorical variable	60695	European	EGG Consortium	31477735
Helicobacter pylori	Binary categorical variable	462933	European	ukb-b-531	/
Esophageal adenocarcinoma	Binary categorical variable	21271	European	ebi-a-GCST003739	27527254
Barrett’s esophagus	Binary categorical variable	56429	European	ebi-a-GCST90000515	25826379
Gastroesophageal reflux disease	Binary categorical variable	467253	European	ebi-a-GCST90018848	34594039

EGG: Early Growth Genetics; GWAS: Genome-wide association study.