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©The Author(s) 2024.
World J Gastrointest Oncol. May 15, 2024; 16(5): 1763-1772
Published online May 15, 2024. doi: 10.4251/wjgo.v16.i5.1763
Published online May 15, 2024. doi: 10.4251/wjgo.v16.i5.1763
Table 1 Basic characteristics of hepatocellular carcinoma patients
Variables | Overall |
Etiology: HBV/others | 118/17 |
Sex: Male/female | 113/22 |
Age (yr) | 53.7 ± 9.8 |
Age: ≥ 60/< 60 yr | 37/98 |
ALT (U/L) | 38.0 (26.0-63.2) |
AST (U/L) | 40.0 (29.4-63.0) |
TBIL (µmol/L) | 14.8 (11.8-20.1) |
ALB (g/L) | 38.9 (34.1-42.0) |
PLT (109/L) | 80 (62-90) |
AFP: ≥ 400/< 400 ng/mL | 43/92 |
Ascites: Yes/no | 29/106 |
Tumor size: > 5/≤ 5 cm | 64/71 |
Tumor number: Multiple/single | 20/115 |
Vascular invasion: Yes/no | 15/120 |
Cirrhosis: Yes/no | 89/46 |
CP grade (A/B) | 113/22 |
ALBI score | -2.53 (-2.76 to -2.15) |
ALBI grade (1/2-3) | 59/76 |
PALBI score | -2.65 (-2.82 to -2.44) |
PALBI grade (1/2-3) | 89/46 |
Table 2 Univariate analysis of factors associated with overall survival and recurrence-free survival of hepatocellular carcinoma patients
Variables | OS | RFS | ||
HR (95%CI) | P value | HR (95%CI) | P value | |
Etiology (HBV/others) | 1.908 (0.755-4.824) | 0.172 | 1.449 (0.687-3.058) | 0.330 |
Sex (male/female) | 1.510 (0.728-3.129) | 0.268 | 1.245 (0.649-2.389) | 0.509 |
Age (> 60/≤ 60 years) | 0.598 (0.297-1.204) | 0.150 | 0.553 (0.292-1.050) | 0.070 |
ALT (> 40/≤ 40 U/L) | 1.250 (0.710-2.198) | 0.441 | 1.272 (0.778-2.083) | 0.786 |
AST (> 40/≤ 40 U/L) | 1.027 (0.585-1.802) | 0.927 | 1.092 (0.672-1.770) | 0.916 |
TBIL (> 17/≤ 17 µmol/L) | 1.411 (0.800-2.487) | 0.234 | 1.156 (0.527-1.418) | 0.566 |
ALB (< 35/≥ 35 g/L) | 1.029 (0.566-1.871) | 0.924 | 1.074 (0.635-1.818) | 0.789 |
AFP (≥ 400/< 400 ng/mL) | 1.881 (1.054-3.357) | 0.032a | 1.863 (1.128-3.077) | 0.015a |
Ascites (yes/no) | 1.692 (0.908-3.152) | 0.098 | 1.788 (1.054-3.033) | 0.031a |
Tumor size (> 5/≤ 5 cm) | 1.919 (1.080-3.411) | 0.026a | 2.189 (1.330-3.602) | 0.002a |
Tumor number (multiple/single) | 1.265 (0.645-2.481) | 0.494 | 1.161 (0.620-2.175) | 0.641 |
Vascular invasion (yes/no) | 2.384 (1.181-4.812) | 0.015a | 2.509 (1.306-4.820) | 0.006a |
Cirrhosis (yes/no) | 1.006 (0.563-1.796) | 0.984 | 1.127 (0.668-1.899) | 0.654 |
CP grade (B/A) | 1.279 (0.654-2.504) | 0.472 | 0.998 (0.533-1.868) | 0.994 |
ALBI grade (2/1) | 2.704 (1.448-5.047) | 0.002a | 1.768 (1.066-2.932) | 0.027a |
PALBI grade (2-3/1) | 1.666 (0.945-2.940) | 0.078 | 1.250 (0.758-2.060) | 0.382 |
- Citation: Man ZR, Gong XK, Qu KL, Pang Q, Wu BQ. Albumin–bilirubin grade as a predictor of survival in hepatocellular carcinoma patients with thrombocytopenia. World J Gastrointest Oncol 2024; 16(5): 1763-1772
- URL: https://www.wjgnet.com/1948-5204/full/v16/i5/1763.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i5.1763