Mitochondrial carrier homolog 2 increases malignant phenotype of human gastric epithelial cells and promotes proliferation, invasion, and migration of gastric cancer cells

Table 1 Relationship between mitochondrial carrier homolog 2 expression and clinical pathological features in gastric cancer patients

Clinical pathological features	n	MTCH2 expression		χ2	P value
		Positive (n = 48)	Negative (n = 17)
Gender
Male	41	27	14	3.673	0.055
Female	24	21	3
Age (yr)
< 60	33	25	8	0.127	0.722
≥ 60	32	23	9
Infiltration depth
T1 + T2	29	16	13	9.454	0.002b
T3 + T4	36	32	4
TNM stage
I + II	34	21	13	5.388	0.020a
III + IV	31	27	4
Lymph node
Metastasis
Yes	45	37	8	5.313	0.021a
No	20	11	9
Greater omentum metastasis
Yes	37	31	6	4.392	0.036a
No	28	17	11
Survival
Yes	44	29	15	4.442	0.035a
No	21	19	2

^aP < 0.05.

^bP < 0.01.

MTCH2: Mitochondrial carrier homolog 2.

Table 2 Correlation between mitochondrial carrier homolog 2 and ATP2A2

Factor	Pearson correlation	P value
MTCH2 and ATP2A2	0.425	< 0.001c

^cP < 0.001.

MTCH2: Mitochondrial carrier homolog 2.