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©The Author(s) 2024.
World J Gastrointest Oncol. Feb 15, 2024; 16(2): 475-492
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.475
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.475
Table 1 Correlation between B56ε expression and hepatocellular carcinoma prognosis
Variables | n | Univariate analysis | Multivariate analysis | ||
HR (95%CI) | P value | HR (95%CI) | P value | ||
Gender | 373 | 1.261 (0.885-1.796) | 0.204 | 1.052 (0.632-1.752) | 0.845 |
Age | 373 | 1.205 (0.850-1.708) | 0.293 | 1.238 (0.768-1.997) | 0.381 |
T | 370 | 2.598 (1.826-3.697) | < 0.001a | 8.023 (0.461-139.715) | 0.153 |
N | 258 | 2.029 (0.497-8.281) | 0.375 | 4.476 (0.583-34.348) | 0.149 |
M | 272 | 4.077 (1.281-12.973) | 0.050 | 1.865 (0.546-6.367) | 0.320 |
Stage | 349 | 2.504 (1.727-3.631) | < 0.001a | 0.357 (0.020-6.488) | 0.487 |
Grade | 368 | 1.091 (0.761-1.564) | 0.637 | 1.177 (0.735-1.885) | 0.498 |
B56ε | 373 | 1.587 (1.120-2.249) | 0.009a | 1.337 (0.829-2.156) | 0.234 |
Table 2 Correlation analysis of B56ε expression with chemotherapy drugs
Drugs | Correlation | P value |
Allopurinol | 0.255 | 0.049 |
Fluorouracil | -0.324 | 0.011 |
Methylprednisolone | 0.279 | 0.031 |
Chelerythrine | 0.334 | 0.009 |
Ergenyl | -0.357 | 0.005 |
Ribavirin | 0.307 | 0.017 |
Claritin | -0.312 | 0.015 |
RAF-265 | -0.293 | 0.023 |
Nelarabine | 0.264 | 0.042 |
PLX-4720 | -0.271 | 0.036 |
Econazole nitrate | 0.316 | 0.014 |
Rabusertib | -0.276 | 0.033 |
Vemurafenib | -0.304 | 0.018 |
Vertex ATR inhibitor Cpd 45 | -0.265 | 0.041 |
Dabrafenib | -0.263 | 0.042 |
- Citation: Wu HM, Huang YY, Xu YQ, Xiang WL, Yang C, Liu RY, Li D, Guo XF, Zhang ZB, Bei CH, Tan SK, Zhu XN. Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(2): 475-492
- URL: https://www.wjgnet.com/1948-5204/full/v16/i2/475.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v16.i2.475