Impact of propofol and sevoflurane anesthesia on cognition and emotion in gastric cancer patients undergoing radical resection

Table 1 Comparison of general data

Group	Propofol (n = 40)	Sevoflurane (n = 40)	χ2/t	P value
Sex			0.05	0.823
Female	19	20
Male	21	20
BMI (kg/m2)	22.85 ± 2.10	22.94 ± 2.12	0.234	0.816
Age (yr)	47.33 ± 5.20	47.82 ± 5.11	0.521	0.604
Body mass (kg)	64.98 ± 5.21	65.01 ± 5.23	0.031	0.975
ASA classes			0.051	0.822
Class Ⅰ	22	23
Class Ⅱ	18	17
Cancer type			2.066	0.559
Adenocarcinoma	23	22
Undifferentiated carcinoma	12	11
Mucinous carcinoma	5	5
Other	0	2
Metastasis			0.155	0.926
Bone metastasis	5	4
Liver metastasis	4	4

BMI: Body mass index; ASA: American Society of Anesthesiologists.

Table 2 Comparison of Loewenstein occupational therapy cognitive assessment scores

Group	T0	T4	t	P value
Propofol (n = 40)	111.98 ± 7.53	90.30 ± 5.25	15.304	< 0.001
Sevoflurane (n = 40)	112.03 ± 6.48	102.32 ± 5.21	7.756	< 0.001
t	0.038	11.711
P value	0.97	< 0.001

Table 3 Comparison of self-rating anxiety scale and self-rating depression scale scores

Group	SAS		SDS
	T0	T4	T0	T4
Propofol (n = 40)	42.29 ± 3.02	51.83 ± 4.49b	44.26 ± 3.50	53.83 ± 4.42
Sevoflurane (n = 40)	42.31 ± 3.86	48.19 ± 4.90b	44.12 ± 3.67	50.13 ± 4.74
t	0.359	5.198	0.639	3.956
P value	0.721	< 0.001	0.525	< 0.001

^bP < 0.01. SAS: Self-rating anxiety scale; SDS: Self-rating depression scale; T₀: Before anesthesia; T₄: 1 d after surgery.