Trends in colorectal cancer incidence according to an increase in the number of colonoscopy cases in Korea

Table 1 The incidence of colorectal cancer by age and gender between 2004 and 2020, n (%)

	2004	2005	2006	2007	2008	2009	2010	2011	2012	2013	2014	2015	2016	2017	2018	2019	2020
Number of patients	15278	17090	20059	20750	21613	24179	24969	28342	29033	28480	27866	27624	29528	29452	29204	30025	27204
Age category (yr)
Male	8948	9999	11709	12283	12786	14347	14991	17112	17530	17086	16674	16462	17680	17497	17479	17877	16178
< 50	1613 (18.0)	1740 (17.4)	1834 (15.7)	1728 (14.1)	1830 (14.3)	1728 (12.0)	1834 (12.2)	2077 (12.1)	2032 (11.6)	1930 (11.3)	1741 (10.4)	1582 (9.6)	1677 (9.5)	1653 (9.4)	1592 (9.1)	1555 (8.7)	1491 (9.2)
50-75	6499 (72.6)	7306 (73.1)	8603 (73.5)	9167 (74.6)	9437 (73.8)	10730 (74.8)	11137 (74.3)	12608 (73.7)	12764 (72.8)	12257 (71.7)	11894 (71.3)	11635 (70.7)	12382 (70.0)	12151 (69.4)	11929 (68.2)	12234 (68.4)	10940 (67.6)
≥ 76	836 (9.3)	953 (9.5)	1272 (10.9)	1388 (11.3)	1519 (11.9)	1889 (13.2)	2020 (13.5)	2427 (14.2)	2734 (15.6)	2899 (17.0)	3039 (18.2)	3245 (19.7)	3621 (20.5)	3693 (21.1)	3958 (22.6)	4088 (22.9)	3747 (23.2)
Female	6330	7091	8350	8467	8827	9832	9978	11230	11503	11394	11192	11162	11848	11955	11725	12148	11026
< 50	1284 (20.3)	1350 (19.0)	1482 (17.7)	1357 (16.0)	1384 (15.7)	1460 (14.8)	1364 (13.7)	1559 (13.9)	1539 (13.4)	1413 (12.4)	1365 (12.2)	1261 (11.3)	1239 (10.5)	1358 (11.4)	1298 (11.1)	1261 (10.4)	1204 (10.9)
50-75	4302 (68.0)	4767 (67.2)	5624 (67.4)	5731 (67.7)	5929 (67.2)	6555 (66.7)	6596 (66.1)	7388 (65.8)	7430 (64.6)	7243 (63.6)	6980 (62.4)	6818 (61.1)	7092 (59.9)	6948 (58.1)	6630 (56.5)	6931 (57.1)	6208 (56.3)
≥ 76	744 (11.8)	974 (13.7)	1244 (14.9)	1379 (16.3)	1514 (17.2)	1817 (18.5)	2018 (20.2)	2283 (20.3)	2534 (22.0)	2738 (24.0)	2847 (25.4)	3083 (27.6)	3517 (29.7)	3649 (30.5)	3797 (32.4)	3956 (32.6)	3614 (32.8)

Table 2 The incidence of preinvasive colorectal cancer by age and gender between 2004 and 2020, n (%)

	2004	2005	2006	2007	2008	2009	2010	2011	2012	2013	2014	2015	2016	2017	2018	2019	2020
Number of patients	165	186	325	598	959	1462	2078	3045	3434	3531	3635	4428	5422	5476	6017	5886	5422
Age category (yr)
Male	96	125	202	380	601	968	1376	1979	2255	2320	2344	2862	3454	3481	3879	3726	3368
< 50	13 (13.5)	22 (17.6)	43 (21.3)	64 (16.8)	90 (15.0)	164 (16.9)	195 (14.2)	269 (13.6)	286 (12.7)	257 (11.1)	292 (12.5)	294 (10.3)	391 (11.3)	348 (10.0)	407 (10.5)	374 (10.0)	327 (9.7)
50-75	79 (82.3)	97 (77.6)	151 (74.8)	299 (78.7)	477 (79.4)	752 (77.7)	1104 (80.2)	1584 (80.0)	1808 (80.2)	1863 (80.3)	1829 (78.0)	2249 (78.6)	2694 (78.0)	2742 (78.8)	2988 (77.0)	2888 (77.5)	2593 (77.0)
≥ 76	4 (4.2)	6 (4.8)	8 (4.0)	17 (4.5)	34 (5.7)	52 (5.4)	77 (5.6)	126 (6.4)	161 (7.1)	200 (8.6)	223 (9.5)	319 (11.1)	369 (10.7)	391 (11.2)	484 (12.5)	464 (12.5)	448 (13.3)
Female	69	61	123	218	358	494	702	1066	1179	1211	1291	1566	1968	1995	2138	2160	2054
< 50	18 (26.1)	14 (23.0)	31 (25.2)	37 (17.0)	69 (19.3)	101 (20.4)	123 (17.5)	192 (18.0)	155 (13.1)	173 (14.3)	181 (14.0)	220 (14.0)	195 (9.9)	236 (11.8)	223 (10.4)	250 (11.6)	236 (11.5)
50-75	45 (65.2)	46 (75.4)	83 (67.5)	164 (75.2)	271 (75.7)	367 (74.3)	527 (75.1)	790 (74.1)	919 (77.9)	917 (75.7)	982 (76.1)	1167 (74.5)	1503 (76.4)	1466 (73.5)	1569 (73.4)	1538 (71.2)	1452 (70.7)
≥ 76	6 (8.7)	1 (1.6)	9 (7.3)	17 (7.8)	18 (5.0)	26 (5.3)	52 (7.4)	84 (7.9)	105 (8.9)	121 (10.0)	128 (9.9)	179 (11.4)	270 (13.7)	293 (14.7)	346 (16.2)	372 (17.2)	366 (17.8)

Table 3 The number of diagnostic colonoscopies (colonoscopy without polypectomy), colonoscopic polypectomies, and the proportion of colonoscopic polypectomies by age between 2002 and 2020

Diagnostic colonoscopy
Age category (yr)	2002	2003	2004	2005	2006	2007	2008	2009	2010	2011
< 50	29611	38996	42182	54209	66858	69898	75540	84326	78133	179675
50-75	48232	64589	74806	98356	126196	144205	167559	203449	225951	467005
≥ 76	2902	3619	4466	5932	7931	9063	10580	13188	15461	28063
Number of patients	80745	107204	121454	158497	200985	223166	253679	300963	319545	674743
Age category (yr)	2012	2013	2014	2015	2016	2017	2018	2019	2020
< 50	181116	174704	174746	182356	200147	222661	238393	270541	272869
50-75	540231	547652	553156	603368	688868	726703	791814	893072	902040
≥ 76	34984	40693	44484	52028	61053	68676	79313	90198	92604
Number of patients	756331	763049	772386	837752	950068	1018040	1109520	1253811	1267513
Colonoscopic polypectomy
Age category (yr)	2002	2003	2004	2005	2006	2007	2008	2009	2010	2011
< 50	6452	7393	9466	14679	21307	26839	32929	38743	40388	96182
50-75	14373	17884	24041	36060	52212	65697	83504	105620	124745	267398
≥ 76	713	863	1156	1748	2769	3376	4444	5764	7393	14924
Number of patients	21538	26140	34663	52487	76288	95912	120877	150127	172526	378504
Age category (yr)	2012	2013	2014	2015	2016	2017	2018	2019	2020
< 50	102224	102977	105681	112414	124598	147501	164400	196231	207971
50-75	324912	337916	347156	382029	440815	484016	544244	635468	668497
≥ 76	19942	24090	27010	32244	37831	44149	52080	61328	65287
Number of patients	447078	464983	479847	526687	603244	675666	760724	893027	941755
The rate of colonoscopic polypectomies
Age category (yr)	2002	2003	2004	2005	2006	2007	2008	2009	2010	2011
< 50	0.179	0.159	0.183	0.213	0.242	0.277	0.304	0.315	0.341	0.349
50-75	0.230	0.217	0.243	0.268	0.293	0.313	0.333	0.342	0.356	0.364
≥ 76	0.197	0.193	0.206	0.228	0.259	0.271	0.296	0.304	0.323	0.347
Age category (yr)	2012	2013	2014	2015	2016	2017	2018	2019	2020
< 50	0.361	0.371	0.377	0.381	0.384	0.398	0.408	0.420	0.433
50-75	0.376	0.382	0.386	0.388	0.390	0.400	0.407	0.416	0.426
≥ 76	0.363	0.372	0.378	0.383	0.383	0.391	0.396	0.405	0.413